基因Ⅶ型新城疫病毒对鸭和SPF鸡致病性比较研究

doi:10.11843/j.issn.0366-6964.2013.12.018

Abstract

Abstract:

Two NDV strains isolated in ducks, Duck/China/SD03/2009 and JSD0812, were used to evaluate the pathogenicity of genotype Ⅶ NDV in ducks and the potential role of ducks in the epidemiology of NDV. Eighty 20-day-old ducks and sixteen 50-day-old SPF chickens were inoculated with Duck/China/SD03/2009 or JSD0812. Ducks of different groups were challenged with NDV intranasally or intramuscularly at the dose of 0.2 and 0.5 mL, respectively. The SPF chickens were infected with NDV intranasally at a dose of 0.1 mL. All of chickens inoculated with NDV had depression, gasping, oral discharges, and greenish-white soft feces and died in 6 days. However, ducks remained clinically normal throughout the study. Viruses were detected more frequently in the swabs and tissues of chickens than ducks. Gross and histologic lesion patterns supported the different clinical outcome. Ducks had slight inflammation mainly in respiratory and digestive tracts, whereas slight nonpurulent encephalitis, tubulointerstitial nephritis, and serious inflammation in respiratory and digestive tracts were detected in chickens. These results showed that both of the NDV strains are virulent in chickens whereas have no obvious pathogenicity in ducks. However, some measures should be taken to prevent virus transmission between ducks and chickens as viruses were detected in swabs of ducks infected with virulent NDV strains.

CLC Number:

S852.659.5

YI Hui, HU Bei-xia, YANG Shao-hua,XU Chuan-tian, HUANG Qing-hua, ZHANG Lin, ZHANG Xiu-mei, WANG Li-li, ZHANG Wei,YUAN Peng, LI Jian-liang, CUI Yan-shun. Pathogenicity Comparison of Newcastle Disease Virus Isolates of Genotype Ⅶ in Ducks and SPF Chickens[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2013, 44(12): 1982-1988.

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Pathogenicity Comparison of Newcastle Disease Virus Isolates of Genotype Ⅶ in Ducks and SPF Chickens

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