内源性逆转录病毒的转录表达与宿主功能关系的研究进展

doi:10.11843/j.issn.0366-6964.2021.08.004

Abstract

Abstract: Endogenous retroviruses (ERVs) are the remains of ancient retroviruses that were infected and integrated into the host genome millions of years ago and inherited through Mendelian law. ERVs have important biological functions and play important roles influencing host phenotype, productivity, embryonic development and immune regulation. In this article, the genomic structure, activity regulation of ERVs by epigenetic modification and integration locus was reviewed. The relation between host embryonic development, immune regulation and ERVs was also discussed. It was expected to provide reference for further exploring the function of endogenous retrovirus in the genome and its influence and evolution in the host.

Key words: endogenous retrovirus, transcriptional regulation, integration locus, immune

CLC Number:

S852.659.3

BAI Shaochuan, ZHANG Lechao, GE Linhan, GUO Yanli, WANG Dehe, LI Lanhui. Research Progress of Relation between Transcriptional Expression of Endogenous Retrovirus and Host Function[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(8): 2107-2114.

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Research Progress of Relation between Transcriptional Expression of Endogenous Retrovirus and Host Function

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