ALV-E的结构、活性调控以及对宿主功能的影响

doi:10.11843/j.issn.0366-6964.2023.07.002

Abstract

Abstract: Avian leukemia virus E subgroup (ALV-E) is an endogenous retroviral element integrated in chicken genome. In recent years, many new ALVEs have been described with the develop-ment of genome sequencing projects. However, the ALV-E effects on host have not been fully understood. In this review, the structure and function of ALV-E were summarized, and the regu-lation of transcription initiation activity of ALV-E was elaborated, and the structure characteristics of ALV-E location in host genome was expounded. Finally, the effects of ALV-E on host function was discussed, which would provide reference for further understanding the function and expression regulation mechanism of avian leukemia virus in the genome of host.

Key words: endogenous retrovirus, biosynthesis, transcriptional regulation, biological function

CLC Number:

S813.1

GUO Yanli, LI Keqiang, BAI Shaochuan, WANG Tao, WANG Dehe, WANG Qi, LI Lanhui. The Structure, Activity Regulation of ALV-E and Its Effects on Host Function[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(7): 2683-2691.

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The Structure, Activity Regulation of ALV-E and Its Effects on Host Function

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