甲型流感病毒NS1、NS2和NS3蛋白的研究进展

doi:10.11843/j.issn.0366-6964.2014.12.001

Abstract

Abstract:

The genome of influenza A virus consists of eight gene segments.Among them，genes of haemagglutinin (HA)，neuraminidase (NA)，nucleoprotein (NP) and PB2 (basic polymerase 2) can only encode single viral protein，respectively.Genes encoding M (matrix protein)，PB1 (basic polymerase 1)，PA (acidic polymerase) and NS (nonstructural protein) proteins can encode more than two viral proteins.This has made the total number of proteins encoded by influenza A virus become 17.It has been found that M gene encodes M1，M2 and M42 proteins，and that PB1 gene encodes PB1，PB1-F2 and PB1-N40 proteins，respectively.PA gene encodes PA，PA-X，PA-N155 and PA-N182，respectively，whereas NS gene encodes NS1，NS2 and NS3 proteins，respectively.It was first reported by M.Selman et al.that a novel viral protein NS3 of influenza A virus was encoded by NS3 mRNA.This review will briefly introduce progress in research on NS1，NS2 and NS3 proteins encoded by influenza A virus NS gene.

CLC Number:

S852.659.5

TAN Wei，XIE Zhi-xun. An Overview of Research Progress on NS1，NS2 and NS3 Proteins of Influenza A Viruses[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(12): 1911-1916.

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An Overview of Research Progress on NS1，NS2 and NS3 Proteins of Influenza A Viruses

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