microRNA调控动物皮下脂肪组织和肌内脂肪沉积的研究进展

doi:10.11843/j.issn.0366-6964.2021.010.002

Abstract

Abstract: Adipose tissues are the important energy metabolism and endocrine organs for animals. Selective fat deposition plays a vital role in the sensory quality, flavor and processing characteristics of animal meat. Therefore, the specific regulatory factors and molecular mechanisms of fat deposition in different parts of animals have attracted the attention of researchers. microRNA (miRNA) was regarded as a family of small non-coding RNA with a length of 22 nt. In recent years, omics technology has been used for high-throughput sequencing of adipose tissues and adipocytes with phenotypic differences, many differentially expressed miRNAs have been screened and found. These miRNAs can perform biological functions by combining with target gene mRNA. The differentially expressed miRNAs in adipose tissues play an important role in the regulation of fat deposition. Here, this review will summarize the function of miRNA involved in subcutaneous adipose tissue and intramuscular adipose tissues of animal, so as to provide theoretical references and new ideas for the further exploration of miRNA regulating on the specific adipose deposition of animal.

Key words: miRNA, fat deposition, subcutaneous adipose tissue, intramuscular fat

CLC Number:

S813.1

YUE Yongqi, HUA Yonglin, XIONG Yan, LIN Yaqiu, XIONG Xianrong, LI Jian. Research Progress of microRNA Regulation on the Fat Deposition of Subcutaneous Adipose Tissue and Intramuscular Fat in Animals[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(10): 2698-2709.

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Research Progress of microRNA Regulation on the Fat Deposition of Subcutaneous Adipose Tissue and Intramuscular Fat in Animals

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