表观遗传调控在畜禽脂肪沉积机制中的研究进展

doi:10.11843/j.issn.0366-6964.2023.03.001

Abstract

Abstract: Epigenetic modifications are heritable changes in gene expression and phenotype without changing in the DNA sequence. Previous studies have shown that epigenetic regulation is involved in many life processes and plays an important role in fat deposition. Moreover, fat deposition is an important factor affecting the meat quality of livestock and poultry. Studying the mechanism of fat deposition is a significant aspect of breeding. In this review, the research progress of DNA methylation, mRNA modification, histone modification, chromosomal remodeling, and non-coding RNA regulation on the mechanism of fat deposition in livestock and poultry were summerized.

Key words: epigenetics, fat deposition, DNA methylation, mRNA modification, histone modification, non-coding RNA

CLC Number:

S852.23

JIN Meilin, LI Taotao, SUN Dongxiao, WEI Caihong. Research Progress of Epigenetic Regulation in Fat Deposition Mechanism of Livestock and Poultry[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(3): 855-867.

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Research Progress of Epigenetic Regulation in Fat Deposition Mechanism of Livestock and Poultry

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[3]	YANG Xiaogeng, ZHANG Huizhu, LI Jian, XIANG Hua, HE Honghong. Research Progress of the DNA Methylation in Mammalian Oocyte and Early Embryo Development [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(2): 443-450.
[4]	WANG Lin, MA Li, ZHANG Bo, DENG Jun, ZHANG Hao, OUYANG Xiaofang, YAN Dawei, DONG Xinxing. Key Genes and Regulatory Network Analysis of Lipid Metabolism Differences between Back Fat and Abdominal Fat of Large Diqing Tibetan Pigs at Different Growth Stages [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(2): 520-533.
[5]	SONG Shuzhen, LIU Junbin, ZHU Caiye, XU Hongwei, LIU Lishan, KONG Yanlong. The Effect of Tail Docking on Growth Performance, Fat Deposition Distribution and Slaughter Performance in Lanzhou Fat-tailed Sheep [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(2): 642-655.
[6]	ZHANG Chenyibo, YU Tong, REN Binbin, ZHENG Ruizhi, ZHU Wenzhi, SU Jianmin. Mechanism of Epigenetic Reprogramming of Early Animal Embryos [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(12): 4898-4909.
[7]	MA Ziming, GUO Xingru, DAI Tianshu, WEI Shihao, SHI Yuangang, DAN Xingang. Research Progress on Regulatory Mechanism of Cattle Uterine Involution and Methods of Promoting Uterine Involution [J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(1): 58-68.
[8]	ZHAI Liwei, ZHAO Yanhui, LI Wenjun, XING Kai, WANG Chuduan. System Analysis of Multi Tissue Transcriptome to Identify Key Genes Affecting Porcine Fat Deposition [J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(6): 1702-1711.
[9]	LIU Yue, XUE Xianglan, LI Xiaobo, JIANG Lin, PU Yabin, HE Xiaohong, MA Yuehui, ZHAO Qianjun. Research Progress of the Relationship between Chromatin Accessibility and Animal Embryo Development [J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(3): 680-687.
[10]	WANG Di, YU Ying. Research Progress on Transcriptomics and Epigenetics of Bovine S. aureus Mastitis Resistance [J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(2): 329-338.
[11]	GAN Jianyu, ZHANG Xin, CAI Gengyuan, HONG Linjun, HUANG Sixiu. Research Progress of DNA Methylation during Porcine Embryonic Development [J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(10): 3287-3295.
[12]	LI Xiong, TIAN Niannian, SONG Linjin, CHEN Chen, XU Houqiang. Effects of 5-Aza-dC on MyoD1 Promoter Methylation and mRNA Expression in Bovine Myoblasts [J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(9): 2439-2451.
[13]	LIU Xiaoqian, JIN Lanjie, DONG Yanqiu, LI Dongjie, ZHANG Cui, GU Shukai, LI Shijie. DNA Methylation Regulate the Genomic Imprinting of AQP1 Gene Specific in Bovine Placenta [J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(8): 2181-2189.
[14]	XUE Qian, LI Guohui, YIN Jianmei, ZHANG Huiyong, ZHOU Chenghao, ZHU Yunfen, XING Weijie, SU Yijun, ZOU Jianmin, HAN Wei. Screening of Genes with Differential Methylated CpG Island Related to Inbreeding Depression of Chicken Reproduction [J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(4): 943-953.
[15]	WANG Yuanxia, LIU Xiuting, ZHANG Xiaojun, XIANG Yun, XU E, LÜ Wentao, YANG Hua, XIAO Yingping. The Developmental Changes of Ileal Microbiota and Fatty Acid Binding Proteins and Its Correlation with Fat Deposition in Jinhua Pigs [J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(3): 723-732.