纳米技术抗耐药菌的研究进展

doi:10.11843/j.issn.0366-6964.2022.11.002

Abstract

Abstract: The problem of bacterial resistance become a common challenge in the world, which leads to a decline in the effect of antimicrobial drugs and a rise in the incidence and mortality of bacterial diseases. The increase of treatment difficulty, expensive therapeutic cost and continuous decrease of animal productivity have caused serious economic losses to animal husbandry. Therefore, it is particularly necessary to find new schemes to fight resistant bacteria. Nanotechnology rose in modern times and has been widely used in many fields, such as biomedicine. It has a significant effect in fighting resistant bacteria, which can reduce bacterial resistance through various mechanisms such as destroy bacterial cell membrane, inhibiting efflux pump, produce reactive oxygen species (ROS) and degrading biofilm. This article will briefly summarize nanotechnology, about its development history, strategies to fight resistant bacteria and mechanisms to fight bacterial resistance, in order to provide some reference for veterinary drug researchers.

Key words: nanotechnology, drug resistance, antibacterial agents, antibacterial mechanism

CLC Number:

S859.7

HONG Mian, HUANG Jiamin, CHEN Dongmei, XIE Shuyu. Research Progress of Nanotechnology to Enhance Antibacterial Efficacy of Antibacterial Drugs[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(11): 3731-3736.

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Research Progress of Nanotechnology to Enhance Antibacterial Efficacy of Antibacterial Drugs

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