猪链球菌耐药现状分析及感染防控措施

doi:10.11843/j.issn.0366-6964.2023.12.004

Abstract

Abstract: Streptococcus suis (S. suis) infection has long plagued the health and sustainable development of our pig industry. In particular, the emergence of drug-resistant strains will block the original prevention and control strategy of streptococcosis. The summary of the prevalence of resistance to S. suis at China and abroad in recent years can provide effective measures for the prevention and treatment of S. suis infection. Therefore, we first summarized the S. suis infection situation in large-scale pig farms at home and abroad in the past five years (most positive rate>40%). Among them, the serotype 2 strain is the most widespread in all provinces and cities in China. Subsequently, we summarized the epidemic status and infection characteristics of drug-resistant S. suis in pig farms, and found that drug-resistant S. suis in large-scale pig farms concentrated in the Asian and Europe, and the drug resistance exceeded 80% in the most regions, mainly tetracycline resistant strains. However, resistance to S. suis in large-scale pig farms in our country is mainly tetracycline and macrolide resistance. In addition, S. suis is a zoonotic agent that can cause systemic infection through the respiratory tract and blood. Finally, in view of the characteristics of S. suis strain variation, we proposed the importance of accurate detection for the prevention and control of S. suis, summarized the rapid detection methods. The prevention and control measures based on vaccination, combined drug use and the development of new host-directed antibiotics are emphasized to provide data support for the subsequent prevention and control of resistant strains of S. suis.

Key words: Streptococcus suis, drug resistance, prevention and control measures

CLC Number:

S852.611

Lü Ruoyi, SI Xiaohui, SUN Zhigang, SHI Xiaomin, LIU Xiaoye. Drug Resistance Situation of Streptococcus suis and Prevention Measures of Infections[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(12): 4920-4933.

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Drug Resistance Situation of Streptococcus suis and Prevention Measures of Infections

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