Acta Veterinaria et Zootechnica Sinica ›› 2021, Vol. 52 ›› Issue (10): 2762-2771.doi: 10.11843/j.issn.0366-6964.2021.010.007

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Research Progress on Antimicrobial Resistance of Clostridium perfringens of Animal Origins

ZHANG Shihong, WANG Shaolin*   

  1. College of Veterinary Medicine, China Agricultural University, Beijing 100193, China
  • Received:2021-01-19 Online:2021-10-23 Published:2021-10-27

Abstract: Antibiotic resistance is one of the most severe threats to public health in the 21st century. As an important zoonotic and food-borne pathogen, Clostridium perfringens (C. perfringens) could cause food poisoning, gas gangrene, necrotizing enteritis in humans and animals. The extensive use of antibiotics promotes the resistance of C. perfringens continuously, seriously threaten the public health and the economic benefits of animal husbandry. This review focuses on the occurrence of antimicrobial resistance in the last decade, and the antibacterial mechanism in C. perfringens of common antibiotics, in a bid to provide scientific insight for the prevention and control of antibiotic resistance.

Key words: Clostridium perfringens, antibiotic resistance, public health

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