Acta Veterinaria et Zootechnica Sinica ›› 2020, Vol. 51 ›› Issue (8): 1775-1783.doi: 10.11843/j.issn.0366-6964.2020.08.001

• REVIEW • Previous Articles     Next Articles

Regulation of Nutrients on the Expression of Endogenous Host Defense Peptide in Animals

CHEN Yonghong1,2, LUO Fang1,2, TAO Jinzhong2, WANG Jing1*   

  1. 1. Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China;
    2. College of Agriculture, Ningxia University, Yinchuan 750021, China
  • Received:2020-02-28 Online:2020-08-25 Published:2020-08-19

Abstract: Host defense peptide is a multifunctional peptide produced by animals. It not only has broad-spectrum antimicrobial function, but also can be used as an innate immune regulator to enhance the body immunity and prevent the invasion of pathogenic microorganisms. It plays an significant role in ensuring animal health. The expression of host defense peptide is regulated by various nutrients in the diet. Some researchers suggested that promoting the expression of host endogenous defense peptide by nutritional regulation was beneficial to the improvement of animal health and production performance, and was one of the possible strategies to achieve antibiotic-free and healthy breeding in the future. In this review, the regulation of endogenous defense peptide expression by various nutrients is discussed comprehensively, which will provide a new theoretical reference for evaluating the effects of nutrients on host immunity and animal health and production.

Key words: host defense peptide, endogenous nutrients, express regulation

CLC Number: