A型流感病毒诱导细胞炎症反应的研究进展

doi:10.11843/j.issn.0366-6964.2024.02.007

Abstract

Abstract: Influenza A virus (IAV) is a respiratory pathogen that can induce inflammatory response in the host. It can induce host inflammatory response and promote the aggregation of inflammatory cells. A large number of inflammatory factors such as chemokines, cytokines, and transcription factors are released, causing excessive host inflammation and eventually leading to cell death and tissue damage. Various proteins encoded by IAV can participate in host inflammatory response through different mechanisms, greatly increasing the morbidity and mortality caused by IAV. A growing body of research suggests that immunomodulatory strategies can improve disease prognosis without affecting the host's resistance to infection. In order to provide new ideas for clinical treatment of IAV infection, this paper reviews the recent progress of IAV-induced inflammatory response.

Key words: influenza A virus, inflammation, immunoregulatory therapy

CLC Number:

S855.3

GAO Xin, SUN Yipeng. Research Progress of Cell Inflammation Induced by Influenza A Virus[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(2): 481-490.

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Research Progress of Cell Inflammation Induced by Influenza A Virus

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