Abstract:

In order to determine the distribution of the oxytocin receptor (OTR) on celiac superior mesenteric ganglion in female goats, we established an immunohistochemical assay in female goats using SP method as the detecting measure of OTR localization in celiac superior mesenteric ganglion in female goats. Our results indicated that OTR immunoreactive substances were distributed in nerve cells, supporting cells and crossing fiber. OTR mainly expressed in the nerve cells, the relative expression of immunoreactive product OTR was extremely significantly compared with other non-nerve cells (P＜0.01). In nerve cells, OTR immunoreactive substances were distributed mainly in the membrane and cytoplasm, but not in the nuclear. The results suggested that neurons in superior mesenteric ganglion had reaction with OT in female goats and OT might regulate the functional activities of the gastrointestinal system by sympathetic nerve from celiac superior mesenteric ganglion.