粪便微生物移植对仔猪肠道屏障功能的影响及作用机制进展

doi:10.11843/j.issn.0366-6964.2021.05.006

Abstract

Abstract: The intestinal barrier is an important defense against infection. Diarrhea in piglets, mainly caused by intestinal biological imbalance and damage of barrier function, has brought extreme losses to the porcine industry. Due to the unique advantages in various intestinal diseases related to intestinal microbiota, faecal microbiota transplantation has been introduced into exploratory researches on the improvement of the intestinal barrier function in piglets as a new microbiota manipulation strategy. This article reviews the structures and functions of the intestinal barrier and the effects of faecal microbiota transplantation on it in piglets, then discusses the possible inner mechanisms, with the expectation to provide some references in this field.

Key words: faecal microbiota transplantation, piglet, intestinal barrier function, mechanism, microbiota

CLC Number:

CHEN Jiaqi, ZHANG Xiaodi, GU Zhaobing, Lü Longbao, WU Dongwang, WANG Rongjiao, MAO Huaming. Effects and Mechanism of Faecal Microbiota Transplantation on Intestinal Barrier Function in Piglets[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(5): 1195-1207.

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Effects and Mechanism of Faecal Microbiota Transplantation on Intestinal Barrier Function in Piglets

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