赤羽病病毒与宿主相互作用机制研究进展

doi:10.11843/j.issn.0366-6964.2025.10.010

Abstract

Abstract:

Akabane virus (AKAV) is a vector-borne pathogen that primarily causes reproductive disorders in ruminants such as cattle and sheep. It is widely distributed in areas where blood- sucking insects such as mosquitoes and midges are concentrated in tropical and temperate regions. The infection situation is particularly severe in some Southeast Asian and East Asian countries. Regional epidemics have been found in China. With the increasing intensification of cattle and sheep farming, frequent trading and transportation, and the expansion of the breeding range of vector insects due to climate change, the disease has a further trend of spreading infection. In this paper, beginning with pathogenic characteristics and tissue tropism of AKAV, the interaction mechanisms between virus infection and the host′s responses were summarized emphatically. It could provide a reference for further exploration of the pathogenesis of AKAV and the development of corresponding therapeutic drugs and preventive preparations.

Key words: Akabane virus, pathogenic mechanism, viral replication, interferon, apoptosis

CLC Number:

S852.65

FENG Yuhuan, ZHANG Yiqian, LIU Xia, ZHOU Xuehui, LIU Yanyan, NIU Luting, NI Xingwei, ZHAO Zhiguo, WANG Yan, YANG Xiaowei, XU Tingting, ZHAO Guangwei. Research Progress on the Interaction Mechanisms between Akabane Virus and Host[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(10): 4877-4888.

Figures/Tables 4

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Research Progress on the Interaction Mechanisms between Akabane Virus and Host

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