N6-腺苷甲基化调控脂肪生成的研究进展

doi:10.11843/j.issn.0366-6964.2025.05.001

Abstract

Abstract:

N6-methyladenosine (m6A) modification is a widely present dynamic reversible modification in eukaryotic mRNA, which plays an important role in regulating lipid metabolism. m6A modification participates in biological processes such as adipocyte differentiation, lipid synthesis and breakdown, by regulating mRNA stability, splicing, transport, and translation. This article systematically reviews the mechanism of m6A modification in regulating adipocyte differentiation, lipid synthesis and breakdown, aiming to provide new strategies for regulating adipogenesis in animals, improving meat quality and promoting the development of animal husbandry.

Key words: N6-methyladenosine, lipid metabolism, adipogenesis, brown fat, lipophage

CLC Number:

S813.1

ZHOU Rui, WU De, CHE Lianqiang, LIN Yan, FENG Bin, FANG Zhengfeng. Advances of N6-Adenosine Methylation Regulating Adipogenesis[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(5): 1995-2003.

Figures/Tables 2

References 67

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Advances of N6-Adenosine Methylation Regulating Adipogenesis

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