微生物-肠-肌轴调节骨骼肌代谢和功能的研究进展

doi:10.11843/j.issn.0366-6964.2022.09.003

Abstract

Abstract: The quality of skeletal muscle not only affects the exercise ability and health state of human or animal, but also affects the production and quality of muscle in livestock and poultry. With the in-depth exploration of microbial functions, gut-brain axis, gut-liver axis, gut-lipid axis and other signaling pathways mediated by microorganisms and their metabolites have been confirmed to participate in the body's energy metabolism. In recent years, microbiota-gut-muscle axis has also been confirmed. Therefore, regulating the metabolism of skeletal muscle by regulating intestinal flora or its metabolites provides a novel insight to improve muscle production and quality. This review mainly summarizes the potential role and preliminary mechanism of intestinal microorganisms and their key metabolites in skeletal muscle function and glucose and lipid metabolism, and briefly summarizes the potential means of regulating flora to control skeletal muscle function, which provides a certain theoretical reference and new ideas for improving meat quality in animal husbandry production.

Key words: microorganism, skeletal muscle, glucose and lipid metabolism, probiotics, exercise

CLC Number:

Q493

ZHOU Min, WANG Kaige, ZHANG Lian, MA Xi. Advances in Microbiota-Gut-Muscle Axis Regulating Skeletal Muscle Metabolism and Function[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(9): 2845-2857.

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Advances in Microbiota-Gut-Muscle Axis Regulating Skeletal Muscle Metabolism and Function

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References 112