Acta Veterinaria et Zootechnica Sinica ›› 2023, Vol. 54 ›› Issue (10): 4040-4049.doi: 10.11843/j.issn.0366-6964.2023.10.004

• REVIEW • Previous Articles     Next Articles

Research Progress on the Mechanism of YY1 and Its Role in the Regulation of Animal Reproduction

XING Wenwen, QI Nannan, LI Mengxuan, LIU Jiying*   

  1. College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China
  • Received:2023-05-11 Online:2023-10-23 Published:2023-10-26

Abstract: The transcription factor Yin-Yang1 (YY1) is a complex protein that regulates important life activities, such as cell proliferation, differentiation, aging, and apoptosis by inhibiting or activating multiple genes expression. YY1 mainly acts as a traditional transcription factor, regulating chromosome structure and phase separation mechanism. It was found that YY1 played an important regulatory role in the reproductive system and was closely related to animal reproductive performance. The article reviews the mechanism of YY1 on gene expression regulation and its role on animal reproductive regulation, which providing a theoretical basis for further research on animal reproductive regulation.

Key words: YY1, transcriptional regulation, ovary, spermatogenesis, reproductive hormone, reproductive regulation

CLC Number: