表观遗传学调控雌性动物初情期启动的研究进展

doi:10.11843/j.issn.0366-6964.2024.05.006

Abstract

Abstract: The puberty of female animals is the period when the estrus appears and ovulation occurs for the first time. The mechanism of puberty onset is complex and closely related to genetic, neuroendocrine, metabolic, nutritional, and environmental factors and so on. However, the specific mechanism of animal puberty onset is still unclear. Recent evidence suggests that epigenetic mechanisms are important coordinators in the process of animal puberty onset. The paper reviews the effects of epigenetic mechanisms such as DNA methylation, histone modification, non-coding RNA, chromatin remodeling, genome imprinting, transcription factor binding, and X chromosome inactivation on the onset of puberty, which provides a reference and basis for the further study of the mechanism of puberty onset in female animals.

Key words: puberty, epigenetic, DNA methylation, histone modification, non-coding RNA

CLC Number:

S813.1

ZHANG Wei, PAN Zhihao, FANG Fugui. Advances in Epigenetic Regulation of the Onset of Puberty in Female Animals[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(5): 1875-1882.

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Advances in Epigenetic Regulation of the Onset of Puberty in Female Animals

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