Acta Veterinaria et Zootechnica Sinica ›› 2022, Vol. 53 ›› Issue (4): 1019-1029.doi: 10.11843/j.issn.0366-6964.2022.04.003

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Research Progress of Milk-derived Exosomes

DING Jun1, FU Zilin1, HE Junhao1, DUAN Xiaowei1, MA Lu1, BU Dengpan1,2,*   

  1. 1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Chinese Academy of Agricultural Sciences and World Agroforestry Center Joint Lab on Agroforestry and Sustainable Animal Husbandry, Beijing 100193, China
  • Received:2021-07-05 Online:2022-04-23 Published:2022-04-25

Abstract: Exosomes are nano-level extracellular vesicles, which are widely present in the tissues and body fluids of a variety of animals. In various types of extracellular vesicles, exosomes can carry multiple compounds with biological activity. At the same time, the sorting of compounds in exosomes is a regulated and non-random process. In recent years, studies have shown that milk-derived exosomes can promote development of the intestinal and immune system of young animals after being absorbed in digestive tract, and they are also involved in some disease processes. This article reviews the production and function of exosomes, the extraction and identification of milk-derived exosomes, as well as their application of milk exosomes, in order to provide the theoretical foundation for further research on milk-derived exosomes.

Key words: milk-derived exosomes, functional characteristics, application

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