铁蛋白纳米载体及其在生物医学领域的应用潜力

doi:10.11843/j.issn.0366-6964.2021.04.007

Abstract

Abstract: Ferritin, an iron storage protein widely found in almost all living organisms, has some main functions of storing and transforming iron, maintaining the balance of cellular iron metabolism and protecting cells from oxidative damage. Ferritin can self-assemble into a spherical nanocage that carries and delivers various metals and a broad range of therapeutic and image agents. Moreover, ferritin has the characteristics of easy modification, good biocompatibility and targeting， and these make ferritin become a non-viral natural nanomaterial with great application potential in the field of biomedicine. This review highlights the structures and biological functions, the current work on ferritin as well as the application prospects based on ferritin nanocarrier platform in the field of disease detection, nanocarrier vaccine and drug carrier in order to provide reference for related researches.

Key words: ferritin, nanocarrier, structure and function, biomedicine, application potential

CLC Number:

R318

SU Kai, FAN Tingli, SONG Qinye. Ferritin Nanocarrier and Its Application Potential in the Field of Biomedicine[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(4): 909-919.

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Ferritin Nanocarrier and Its Application Potential in the Field of Biomedicine

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