CRISPR/Cas9技术及其在猪基因编辑中的应用

doi:10.11843/j.issn.0366-6964.2020.03.001

Abstract

Abstract: CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 9) is a novel editing system, which is originally developed from the bacteria defense immune mechanism against viruses infection and plasmid transfer. As a simple, accurate, economical and efficient tool, this technology has been extensively used in the gene-editing and related research fields. The progress and application of CRISPR/Cas9 technology in pig genome editing in the past few years are summarized in this review, and also discusses its future perspectives in pig breeding and clinical trials.

Key words: CRISPR/Cas9, genome editing, pig, application

CLC Number:

S828.2

LIU Siyuan, LU Dan, TANG Zhonglin. Research Progress on CRISPR/Cas9 and Its Application in Pigs Genome Editing[J]. Acta Veterinaria et Zootechnica Sinica, 2020, 51(3): 409-416.

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Research Progress on CRISPR/Cas9 and Its Application in Pigs Genome Editing

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