外源性硫化氢的毒性机制及在动物体内代谢的研究进展

doi:10.11843/j.issn.0366-6964.2021.05.003

Abstract

Abstract: Exogenous hydrogen sulfide (H₂S), a malodorous gas, is released during decomposition of sulfur-containing organic matter in livestock and poultry production. Long-term exposure to H₂S damages central nervous system, irritates eye and respiratory organs, inhibits cytochrome oxidase activity, and even directly depresses the respiratory center, which causes acute and chronic poisoning. Moreover, high concentrations of hydrogen sulfide can quickly lead to asphyxia and death in human and animals. Thus, H₂S seriously affect the livestock and poultry production, animal welfare and human health. However, little is known about the prevention and treatment of hydrogen sulfide poisoning. Therefore, in-depth study of the absorption and metabolism of exogenous hydrogen sulfide in animals and clarification of its mechanism are of great significance to alleviate the harm of hydrogen sulfide in livestock and poultry production. This paper reviews the current research on the characteristics, absorption, metabolism and toxicity of H₂S for the purpose of proving a reference for further research on the mechanism by which H₂S affects animal health and a theoretical foundation for animal healthy breeding.

Key words: hydrogen sulfide, animal, toxicity, harm, absorption, metabolism

CLC Number:

S852.2

XIE Yanjiao, LIU Zhen, CHEN Lei, MIAO Qixiang, ZHANG Hongfu, TANG Xiangfang. Research Progress on Toxicity Mechanism and Metabolism of Exogenous Hydrogen Sulfide[J]. Acta Veterinaria et Zootechnica Sinica, 2021, 52(5): 1163-1170.

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Research Progress on Toxicity Mechanism and Metabolism of Exogenous Hydrogen Sulfide

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