SNP遗传力估计方法、影响因素及其在畜禽育种中的应用

doi:10.11843/j.issn.0366-6964.2024.05.004

Abstract

Abstract: Heritability is a measure of the proportion of phenotypic variance explained by genetic factors. In actual heritability evaluation, only additive genetic effects are considered. With the development of genomics, genome-wide single nucleotide polymorphisms (SNPs) have been widely used to evaluate heritability because of the difficulty in achieving the integrity and accuracy of genealogy information that traditional heritability estimation relies on. However, accurate evaluation of SNP heritability is helpful in understanding the extent of genetic variation’s effect on phenotype. Currently, many SNP heritability evaluation models have been developed and utilized. In this paper, the concept, common evaluation methods and influencing factors of SNP heritability are reviewed, and a comparison was made between SNP heritability and the traditional heritability estimation, in order to explore the potential application of SNP heritability in livestock breeding.

Key words: SNP heritability, loss of heritability, influencing factors, estimation model, farmer animal breeding

CLC Number:

S813

DUAN Yixin, ZHANG Linyun, ZHAO Yongju. The Evaluated Methods and Influencing Factors of SNP Heritability and Its Application in Farmer Animal Breeding[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(5): 1854-1865.

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The Evaluated Methods and Influencing Factors of SNP Heritability and Its Application in Farmer Animal Breeding

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