畜牧兽医学报 ›› 2023, Vol. 54 ›› Issue (3): 868-876.doi: 10.11843/j.issn.0366-6964.2023.03.002
冯肖艺1,2, 杨柏高1, 郝海生1, 杜卫华1, 朱化彬1, 崔凯2*, 赵学明1*
收稿日期:
2022-08-30
出版日期:
2023-03-23
发布日期:
2023-03-21
通讯作者:
赵学明,主要从事家畜胚胎生物技术研究,E-mail:zhaoxueming@caas.cn;崔凯,主要从事动物遗传育种与繁殖学研究,E-mail:qdndcuikai@163.com
作者简介:
冯肖艺(1999-),女,山东济南人,硕士生,主要从事动物繁殖研究,E-mail:17806257712@163.com
基金资助:
FENG Xiaoyi1,2, YANG Baigao1, HAO Haisheng1, DU Weihua1, ZHU Huabin1, CUI Kai2*, ZHAO Xueming1*
Received:
2022-08-30
Online:
2023-03-23
Published:
2023-03-21
摘要: 乳制品是人们生活中补充优质蛋白质的重要来源,其营养价值极高,对身体健康益处多多。日益增长的乳制品消费需求给奶业生产带来了机遇和挑战,提高奶牛的生产效率已成为研究热点。然而,现代奶业生产面临诸多困境,如夏季高温导致奶牛热应激,造成奶牛繁殖力下降。奶牛热应激对胚胎质量具有不利影响,包括胚胎细胞周期进程和细胞存活,导致胚胎质量下降,生产效率降低。此外,表观遗传修饰异常是奶牛热应激影响胚胎质量的另一机制,主要包括组蛋白修饰异常和DNA甲基化异常。大量研究表明,恢复细胞线粒体功能和使用褪黑素可以有效缓解热应激对胚胎的不良影响。因此,本文概述了热应激导致胚胎表观遗传修饰异常从而导致胚胎质量下降的机制,以及通过线粒体移植和褪黑素处理来缓解热应激以提高胚胎质量的两种解决措施,从而有利于提高奶牛的生产效率,以期为降低热应激对畜牧业造成的损失提供参考。
中图分类号:
冯肖艺, 杨柏高, 郝海生, 杜卫华, 朱化彬, 崔凯, 赵学明. 热应激导致奶牛胚胎质量下降的机制及解决措施[J]. 畜牧兽医学报, 2023, 54(3): 868-876.
FENG Xiaoyi, YANG Baigao, HAO Haisheng, DU Weihua, ZHU Huabin, CUI Kai, ZHAO Xueming. Mechanism and Solution of Heat Stress Induced Embryo Quality Decline in Dairy Cows[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(3): 868-876.
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