猴头菇多糖对呼肠孤病毒感染番鸭肠道黏膜免疫及抗氧化能力的影响

doi:10.11843/j.issn.0366-6964.2015.09.025

Abstract

Abstract:

The aim of this study was to reveal the effect of Hericium erinaceus polysaccharide(HEP) on the intestinal mucosal immune and antioxidant capacity of ducklings which were infected with muscovy duck reovirus(MDRV).Through the establishment of simulation model which was similar with MDRV natural infection，200 of 1-day-old healthy ducklings were randomly divided into blank control group，HEP control group，cohabitation infected control group and HEP prevention group.The samples from ducklings in each experimental group were collected and determined in the first day，the third day，the sixth day，the tenth day，the fifteenth day and the twenty-first day after cohabitation infection.The results showed that，HEP could promote the secretion of SIgA，IFN-γ and IL-4 on intestinal of infected MDRV ducklings in different degree，also with the maintenance of intestinal mucosal immune balanced effect，and increased SOD activity and GSH content，decreased the content of MDA significantly，it turned out to have the function of improving antioxidase activity，removing free radicals and inhibiting lipid peroxidation.These results indicated that HEP had certain effect on regulating intestinal mucosal immunity of the ducklings and also improving the ability of anti-oxidation，reducing the intestinal barrier function which was damaged by MDRV effectively.

CLC Number:

S859.7

HUANG Li-na，JIANG Hui-hui，WANG Jie，GAO Ting，ZHANG Ye-fei，WU Bao-cheng，WU Yi-jian，HUANG Yi-fan. Effects of Hericium erinaceus Polysaccharide on Intestinal Mucosal Immune and Antioxidant Capacity of Muscovy Ducks Infected with Reovirus[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2015, 46(9): 1671-1677.

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References

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Effects of Hericium erinaceus Polysaccharide on Intestinal Mucosal Immune and Antioxidant Capacity of Muscovy Ducks Infected with Reovirus

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