枯草芽孢杆菌和猪源乳酸杆菌混合饲喂对仔猪肠绒毛发育的影响

Abstract

Abstract:

This study focused on the effects of co-administration of Bacillus subtilis RJGP16 and porcine Lactobacillus salivarius B1 on intestinal villus of piglets, as well as the antagonism between the probiotics and Escherichia coli K88 in vivo. Eight litters newborn piglets were orally administrated with B. subtilis (viable count 1.0×10⁹ CFU·mL^-1), procine L. salivarius (viable count 1.0×10⁹CFU·mL^-1), these two kinds of probiotics (volume ratio 1:1) respectively, at 0, 7, 11 and 26 days after birth. After co-administration of the two probiotics, the piglets were inoculated with E. coli K88. The results showed that the co-administration of the two probiotics could significantly promote the villus height (VH) of duodenum (P<0.05) and ileum (P<0.01), increase the villus number of duodenum (P<0.05) and jejunum (P<0.01), lower the crypt depth (CD) of jejunum (P<0.05) and ileum (P<0.01), and increase the villus height/crypt depth (VH/CD) of duodenum (P<0.05), jejunum (P<0.05) and ileum (P<0.01). In addition, the co-administration of the two probiotics could effectively antagonize the injury caused by E. coli K88 to intestinal epithelium of piglets. These results suggested that the B. subtilis and L. salivarius could promote the development of the intestinal villus and increase the resistance to infection.

CLC Number:

S852.16

DENG Jun, LI Yun-feng, YANG Qian. Effects of Co-Administration of Bacillus subtilis and Porcine Lactobacillus salivarius on Intestinal Villus of Piglets[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, doi: .

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Effects of Co-Administration of Bacillus subtilis and Porcine Lactobacillus salivarius on Intestinal Villus of Piglets

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