Acta Veterinaria et Zootechnica Sinica ›› 2025, Vol. 56 ›› Issue (12): 6046-6059.doi: 10.11843/j.issn.0366-6964.2025.12.010

• REVIEW • Previous Articles     Next Articles

Biological Functions of the Animal Herpesvirus pUL7

LAN Xing1, WANG Mingshu1,2*, CHENG Anchun2,3,4   

  1. 1. Institute of Veterinary Medicine and Immunology, Sichuan Agricultural University, Chengdu 611130, China;
    2. Key Laboratory of Animal Disease and Human Health of Sichuan Province, Chengdu 611130, China;
    3. Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu 611130, China;
    4. International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province, Chengdu 611130, China
  • Received:2025-02-19 Published:2025-12-24

Abstract: The UL7 gene is highly conserved among members of the Herpesviridae family, and its encoded pUL7 protein plays a critical biological role in the pathogenic regulation of viral infection. This review systematically outlines the structural characteristics of the UL7-encoded protein and comprehensively summarizes the functions of pUL7 in key stages of the viral life cycle, including review systematically summarizes the structural characteristics of UL7-encoded proteins and the replication, transcription, protein expression, virion assembly, and release. Additionally, it explores the interaction mechanisms between pUL7 and other viral or host proteins, aiming to provide valuable insights for further research on the UL7 gene in herpesviruses.

Key words: herpes virus, UL7 protein, protein structure, function

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