Acta Veterinaria et Zootechnica Sinica ›› 2021, Vol. 52 ›› Issue (8): 2083-2092.doi: 10.11843/j.issn.0366-6964.2021.08.002

• REVIEW • Previous Articles     Next Articles

Research Progress on the Correlation between Gastrointestinal Microbiota and Bovine Mastitis in Dairy Cows and Its Regulatory Potential for Mastitis

WANG Yue1, NAN Xuemei1, JIANG Linshu2*, XIONG Benhai1*   

  1. 1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Key Laboratory of Dairy Nutrition in Beijing, Animal Sciences and Technology College, Beijing University of Agriculture, Beijing 102206, China
  • Received:2021-01-21 Online:2021-08-23 Published:2021-08-21

Abstract: Bovine mastitis is one of the diseases that seriously affect the body health status and milk quality of dairy cows. The infection of mammary gland caused by the invasion of exogenous pathogenic bacteria has long been considered to be the main factor of bovine mastitis. However, recent studies have shown that the gastrointestinal microorganisms can also influence and regulate the development of mastitis. The main mechanism may involve the entero-mammary pathway, that is, certain bacteria from the gastrointestinal tract may migrate to the mammary gland via an endogenous cellular pathway through a mechanism involving monocytes (mainly phagocytes). In this review, the pathogenic factors of bovine mastitis and its influence, the relationship between gastrointestinal microflora and mastitis as well as the regulation of gastrointestinal microbiome on mastitis (including dietary, short-chain fatty acids (SCFAs), probiotics and commensal bacteria) etc., were reviewed, aiming to provide several new information for the pathogenesis and mitigation measures of bovine mastitis.

Key words: dairy cow, mastitis, gastrointestinal microbiota, entero-mammary endogenous pathway

CLC Number: