胃肠道菌群与黏膜免疫在围产期奶牛健康中的作用

doi:10.11843/j.issn.0366-6964.2023.07.009

Abstract

Abstract: The changes of gastrointestinal flora play an important role in animal health and disease, and more and more research evidence has linked the immune system with gastrointestinal flora. The main mechanism may be that the disturbance of flora leads to the imbalance of flora-immune interaction, the imbalance of nutritional metabolism and energy regulation, the damage of immune system, and finally induces disease. Perinatal dairy cows face the severe challenge of maintaining normal physiological metabolism. Dairy cows are easy to be infected with a variety of diseases during the perinatal period, which brings serious economic losses to the pasture. Recent studies have shown that the disturbance of rumen flora in perinatal dairy cows is an important cause of productive diseases, and the dynamic interaction between gastrointestinal flora and host mucosal immune system plays a key role in maintaining gastrointestinal dynamic balance and inhibiting inflammation. In this paper, the changes of gastrointestinal microflora and the composition of gastrointestinal mucosal immune system in perinatal dairy cows were reviewed, and the important role of the interaction mechanism of microflora and mucosal immunity in maintaining the health of dairy cows was discussed. Finally, the productive diseases of dairy cows mediated by flora disorder and immune imbalance were introduced in order to provide new ideas for perinatal cow feeding and management and disease prevention and control.

Key words: perinatal dairy cows, gastrointestinal microbiota, mucosal immunity, dysbacteriosis

CLC Number:

S857.2

ZHAO Wanli, CAO Qiqi, YANG Yue, DENG Zhaoju, XU Chuang. The Interaction between Gastrointestinal Microbiota and Mucosal Immunity in Health of Perinatal Dairy Cows[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(7): 2751-2760.

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The Interaction between Gastrointestinal Microbiota and Mucosal Immunity in Health of Perinatal Dairy Cows

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