细胞死亡的新方式——铁死亡与铜死亡

doi:10.11843/j.issn.0366-6964.2024.02.005

Abstract

Abstract: Cuproptosis is a newly discovered form of regulated cell death (RCD), which is regulated by the accumulation of copper ions in cells, a process that is targeted to the tricarboxylic acid (TCA) cycle. Although the basic molecular mechanism has been elucidated by scholars, there are still many aspects to be studied. In contrast, ferroptosis induced by ferric ion overload is relatively well-studied. In this paper, the research on ferroptosis is used as a reference to compare with cuproptosis, and the cell death induced by two metal ions is reviewed thoroughly.

Key words: ferroptosis, cuproptosis, molecular mechanism, state of disease

CLC Number:

S852.3

WANG Hao, XIAO Jinlong, SHEN Jue, ZHAO Jingang, WANG Shuai, LIU Gen, ZHAO Ru, XIAO Peng, GAO Hong. New Ways of Cell Death—Ferroptosis and Cuproptosis[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(2): 461-470.

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New Ways of Cell Death—Ferroptosis and Cuproptosis

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