Acta Veterinaria et Zootechnica Sinica ›› 2021, Vol. 52 ›› Issue (5): 1154-1162.doi: 10.11843/j.issn.0366-6964.2021.05.002

• REVIEW • Previous Articles     Next Articles

Research Progress of Extracellular Vesicles Regulating Mammalian Embryo Implantation

ZHANG Rong, ZHAO Le, YANG Haili, YANG Yongheng, CHENG Wenqiang, ZHAO Yongju*   

  1. Chongqing Engineering Research Center for Herbivores Resource Protection and Utilization, Chongqing Key Laboratory of Herbivore Science, College of Animal Science and Technology, Southwest University, Chongqing 400715, China
  • Received:2020-07-20 Online:2021-05-23 Published:2021-05-22

Abstract: As a kind of cell communication mediator, extracellular vesicles can interact with target cells/target tissues through miRNA, protein and other molecules carried by them, and influence the functions and phenotypes of target cells/target tissues. Recent studies have shown that extracellular vesicles from the embryo, endometrium and uterine microenvironment are involved in the process of mammalian embryo implantation, thereby ensuring successful embryo implantation, fetal growth and development by affecting endometrium receptivity and trophoblast cell adhesion. This article mainly discusses the occurrence, biological function and role of extracellular vesicles in the process of mammalian embryo implantation.

Key words: extracellular vesicles, mammal, uterus, embryo implantation

CLC Number: