畜牧兽医学报 ›› 2025, Vol. 56 ›› Issue (12): 5972-5986.doi: 10.11843/j.issn.0366-6964.2025.12.004

• 综述 • 上一篇    下一篇

细胞外囊泡在猪繁殖中的研究进展

张小芳1,4, 祝媛媛1, 黄雯卉1, 甘霖生1, 刘杰2,3,4, 魏立民2,3,4, 柒启恩1*   

  1. 1. 佛山大学动物科技学院, 佛山 528225;
    2. 海南省农业科学院三亚研究院(海南省实验动物研究中心), 三亚 572025;
    3. 海南省农业科学院畜牧兽医研究所, 海口 571100;
    4. 海南省热带动物繁育与疫病研究重点实验室, 海口 571100
  • 收稿日期:2025-04-18 发布日期:2025-12-24
  • 通讯作者: 柒启恩,主要从事动物生理生化与分子营养、饲料加工工艺研究,E-mail:qiqien@fosu.edu.cn
  • 作者简介:张小芳(1996-),女,贵州德江人,硕士生,主要从事动物营养与饲料的研究,E-mail:2819831857@qq.com
  • 基金资助:
    国家自然科学基金(31902228);海南省热带动物繁育与疫病研究重点实验室开放课题(HAASXM2025HKL03)

Research Progress of Extracellular Vesicles in Porcine Reproduction

ZHANG Xiaofang1,4, ZHU Yuanyuan1, HUANG Wenhui1, GAN Linsheng1, LIU Jie2,3,4, WEI Limin2,3,4, QI Qien1*   

  1. 1. College of Animal Science and Technology, Foshan University, Foshan 528225, China;
    2. Sanya Research Institute of Hainan Academy of Agricultural Sciences, Sanya 572025, China;
    3. Institute of Animal Husbandry and Veterinary Medicine, Hainan Academy of Agricultural Sciences, Haikou 571100, China;
    4. Key Laboratory of Tropical Animal Breeding and Disease Research, Haikou 571100, China
  • Received:2025-04-18 Published:2025-12-24

摘要: 细胞外囊泡(extracellular vesicles,EVs)属于细胞分泌衍生的膜结构,是细胞间信息物质传递的载体,在动物生殖过程中发挥着关键作用。哺乳动物繁殖是一个较为复杂的过程,受多种因素调控。随着对EVs在动物繁殖中研究的不断深入,其在猪繁殖中的应用也逐渐展现出巨大潜力。EVs主要通过参与多种生理功能来实现生殖过程中的平衡,确保猪繁殖过程中配子发生、受精、囊胚植入、胚胎着床及分娩等环节的顺利进行。本文对EVs的生物学特征及其在猪繁殖各阶段的作用进行了综述,旨在为EVs在猪繁殖中的研究应用提供一定的理论参考。

关键词: 细胞外囊泡, 猪, 繁殖

Abstract: Extracellular vesicles (EVs) belong to the membrane structure derived from cell secretion, which are the carriers of information material transfer between cells, playing crucial roles in mammalian reproduction process. Mammalian reproduction is a rather complex process, regulated by multiple factors. With the continuous deepening of the research on EVs in animal reproduction, their application in pig reproduction has gradually demonstrated great potential. EVs mainly achieve balance in the reproductive process by participating in a variety of physiological functions, ensuring the smooth progress of gametogenesis, fertilization, blastocyst implantation, embryo implantation, and delivery in the process of pig reproduction. This article reviews the biological characteristics of EVs and their roles in various porcine reproduction stages, aiming to provide some theoretical reference for deep research and application of EVs in porcine reproduction.

Key words: extracellular vesicles, porcine, reproduction

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