氨基葡萄糖对断奶仔猪血清抗氧化、炎症指标以及肠道微生物的影响

doi:10.11843/j.issn.0366-6964.2025.08.029

畜牧兽医学报 ›› 2025, Vol. 56 ›› Issue (8): 3908-3921.doi: 10.11843/j.issn.0366-6964.2025.08.029

氨基葡萄糖对断奶仔猪血清抗氧化、炎症指标以及肠道微生物的影响

孟亚轩¹^,²^,³(), 刘彦²^,³, 王晶²^,³, 陈国顺¹^,*(), 冯涛¹^,²^,³^,*()

1. 甘肃农业大学动物科学技术学院, 兰州 730070
2. 北京市农林科学院畜牧兽医研究所, 北京 100097
3. 北京市农林科学院-美国俄克拉荷马州立大学动物科学联合实验室, 北京 100097

收稿日期:2024-09-19 出版日期:2025-08-23 发布日期:2025-08-28
通讯作者: 陈国顺,冯涛 E-mail:18793606358@163.com;chengs@gsau.edu.cn;fengtao@baafs.net.cn
作者简介:孟亚轩(2000-)，女，甘肃金昌人，硕士生，主要从事家畜生产营养调控研究，E-mail：18793606358@163.com
基金资助:
国家自然科学基金(31972575)；兰州市人才创新创业项目专项—数字化无抗甘味畜产品生产技术成果应用与推广(23-3-110)

Effects of Glucosamine on Serum Anti-oxidation, Inflammatory Indexes and Intestinal Microbes in Weaned Piglets

MENG Yaxuan¹^,²^,³(), LIU Yan²^,³, WANG Jing²^,³, CHEN Guoshun¹^,*(), FENG Tao¹^,²^,³^,*()

1. College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China
2. Institute of Animal Husbandry and Veterinary Medicine (IAHVM), Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing 100097, China
3. Joint Laboratory of Animal Science between IAHVM of BAAFS and Division of Agricultural Science and Natural Resource of Oklahoma State University, Beijing 100097, China

Received:2024-09-19 Online:2025-08-23 Published:2025-08-28
Contact: CHEN Guoshun, FENG Tao E-mail:18793606358@163.com;chengs@gsau.edu.cn;fengtao@baafs.net.cn

摘要/Abstract

摘要：

旨在研究氨基葡萄糖(glucosamine，GlcN)对断奶仔猪血清抗氧化、炎症指标以及肠道微生物的影响。试验选取250头体重相近21日龄的健康“杜×长×大”断奶仔猪，随机分为5个处理组，每组5个重复，每个重复10头猪，试验期14 d。分别饲喂基础日粮(NC组)、基础日粮+金霉素75 mg·kg^-1(PC组)、基础日粮+GlcN 1 g·kg^-1(G1组)、基础日粮+GlcN 2 g·kg^-1(G2组)和基础日粮+GlcN 3 g·kg^-1(G3组)，在试验14 d每组随机选择两个重复采集仔猪的血清和粪便样品，检测血清氧化应激和炎症相关指标，解析粪便微生物群构成，并对血清指标和微生物组成做相关性分析。结果表明：1)GlcN添加能够改变血清丙二醛(MDA)含量、总抗氧化能力(T-AOC)以及过氧化氢酶(CAT)和总超氧化物歧化酶(T-SOD)活性，改变炎症指标白细胞介素-10(IL-10)、白细胞介素1β(IL-1β)水平；2)GlcN添加能够影响肠道微生物组成，在门水平上，各组中占比前三的菌门为厚壁菌门(Firmicutes)、拟杆菌门(Bacteroidota)和螺旋体门(Spirochaetota)；在属水平上，与NC组相比，G2组瘤胃球菌科UCG-002属细菌丰度显著降低，并且与T-SOD呈显著负相关(P＜0.05)；G3组norank_f_Eubacterium_coprostanoligenes_group丰度显著降低(P＜0.05)；G1组norank_f_Ruminococcaceae丰度显著增加(P＜0.05)；G2组毛螺菌科Dorea属细菌与T-SOD呈显著正相关、G3组Dorea与IL-6呈显著负相关(P＜0.05)；在G2组中Christensenellaceae_R-7_group与肿瘤坏死因子-α(TNF-α)呈显著负相关，在G3组中与T-SOD呈显著正相关(P＜0.05)；GlcN添加后仔猪肠道中与抗氧化指标和抗炎指标相关性均较大的微生物属有UCG-002、Dorea和Christensenellaceae_R-7_group。综上所述，GlcN能够增强断奶仔猪的抗氧化能力、抗炎功能以及调节肠道微生物菌群的组成共同缓解断奶应激。

关键词: 氨基葡萄糖, 断奶仔猪, 肠道菌群, 微生物, 饲养试验

Abstract:

The study aimed to investigate the effects of glucosamine (GlcN) on serum antioxidant and inflammatory indexes and intestinal microbiota in weaned piglets. A total of 250 healthy 21-day-old weaned "Duroc×Landrace×Yorkshire" piglets, with similar body weights, were randomly allocated into five treatment groups. Each group consisted of five replicates with ten piglets per replicate. The trial duration was 14 days. The piglets were fed with the following diets: basal diet (NC group), basal diet + 75 mg·kg^-1 chlortetracycline (PC group), basal diet + 1 g·kg^-1 g GlcN (G1 group), basal diet + 2 g·kg^-1 GlcN (G2 group), and basal diet + 3 g·kg^-1 GlcN (G3 group). At the end of the 14-day trial, two replicates were randomly selected from each group to collect serum and fecal samples. These samples were then subjected to assessments of serum oxidative stress and inflammation-related biomarkers, analysis of fecal microbiota composition, and correlation analysis between serum indicators and microbial composition. The results indicated that: 1) GlcN supplementation can change serum oxidative stress-related index MDA (malondialdehyde), T-AOC (total antioxidant capacity), CAT (catalase), T-SOD (total superoxide dismutase) and index of immune function IL-10 (interleukin-10) and IL-1β (interleukin-1beta). 2) GlcN supplementation can influence intestinal microbial flora. At the phylum level, the top three most abundant bacterial phyla were Firmicutes, Bacteroidota, and Spirochaetota. At the genus level, compared to the NC group, the abundance of Ruminococcaceae UCG-002 was significantly reduced and showed a significant negative correlation with T-SOD (P < 0.05) in the G2 group, the abundance of norank_f_Eubacterium_coprostanoligenes_group was reduced in the G3 group (P < 0.05). The abundance of norank_f_Ruminococcaceae increased in the G1 group (P < 0.05). Specifically, Lachnospiraceae Dorea in the G2 group showed a significant positive correlation with T-SOD, whereas in the G3 group, it exhibited a significant negative correlation with IL-6 (P < 0.05). Additionally, Christensenellaceae_R-7_group was negatively correlated with TNF-α (tumor necrosis factor-α) in the G2 group (P < 0.05), while it displayed a significant positive correlation with T-SOD in the G3 group (P < 0.05). After GlcN supplementation, three genera including UCG-002, Dorea and Christensenellaceae_R-7_group in piglet intestine were closely related to both antioxidant and anti-inflammatory indexes. In summary, GlcN can enhance the antioxidant capacity and immune function, and regulate intestinal microbiota together to alleviate weaning stress in piglets.

Key words: glucosamine, weaned piglets, intestinal flora, microorganisms, feeding experiment

中图分类号:

孟亚轩, 刘彦, 王晶, 陈国顺, 冯涛. 氨基葡萄糖对断奶仔猪血清抗氧化、炎症指标以及肠道微生物的影响[J]. 畜牧兽医学报, 2025, 56(8): 3908-3921.

MENG Yaxuan, LIU Yan, WANG Jing, CHEN Guoshun, FENG Tao. Effects of Glucosamine on Serum Anti-oxidation, Inflammatory Indexes and Intestinal Microbes in Weaned Piglets[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(8): 3908-3921.

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参考文献 39

1	WU S N , WANG L , CUI B L , et al. Effects of vitamin a on growth performance, antioxidants, gut inflammation, and microbes in weaned piglets[J]. Antioxidants (Basel), 2023, 12 (12): 2049. doi: 10.3390/antiox12122049
2	TUN H M , PENG Y , MASSIMINO L , et al. Gut virome in inflammatory bowel disease and beyond[J]. Gut, 2024, 73 (2): 350- 360. doi: 10.1136/gutjnl-2023-330001
3	YIN C , WEN X B , DANG G Q , et al. Modulation of pectin on intestinal barrier function via changes in microbial functional potential and bile acid metabolism[J]. J Nutr Biochem, 2024, 124, 109491. doi: 10.1016/j.jnutbio.2023.109491
4	TANG W J , NI Z X , WEI Y S , et al. Extracellular vesicles of Bacteroides uniformis induce M1 macrophage polarization and aggravate gut inflammation during weaning[J]. Mucosal Immunol, 2024, 17 (5): 793- 809. doi: 10.1016/j.mucimm.2024.05.004
5	YANG Q L , HUANG X Y , WANG P F , et al. Longitudinal development of the gut microbiota in healthy and diarrheic piglets induced by age-related dietary changes[J]. Microbiologyopen, 2019, 8 (12): e923. doi: 10.1002/mbo3.923
6	SUN J , DU L , LI X L , et al. Identification of the core bacteria in rectums of diarrheic and non-diarrheic piglets[J]. Sci Rep, 2019, 9 (1): 18675. doi: 10.1038/s41598-019-55328-y
7	陈婷, 崔亚东, 兰伟, 等. 氨基葡萄糖的功能及其在动物生产中的应用[J]. 畜牧兽医学报, 2025, 56 (4): 1518- 1526. doi: 10.11843/j.issn.0366-6964.2025.04.005
	CHEN T , CUI Y D , LAN W , et al. Function of glucosamine and its application in animal production[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56 (4): 1518- 1526. doi: 10.11843/j.issn.0366-6964.2025.04.005
8	刘彬, 刘彦, 郑琛, 等. 氨基葡萄糖对断奶仔猪生长性能、抗氧化能力及免疫功能的影响[J]. 畜牧兽医学报, 2024, 55 (7): 3246- 3254. doi: 10.11843/j.issn.0366-6964.2024.07.042
	LIU B , LIU Y , ZHENG C , et al. Effects of glucosamine on growth performance, antioxidant capacity, and immune function in weaned piglets[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55 (7): 3246- 3254. doi: 10.11843/j.issn.0366-6964.2024.07.042
9	GARDINER G E , METZLER-ZEBELI B U , LAWLOR P G . Impact of intestinal microbiota on growth and feed efficiency in pigs: A review[J]. Microorganisms, 2020, 8 (12): 1886. doi: 10.3390/microorganisms8121886
10	BIAN G R , MA S Q , ZHU Z G , et al. Age, introduction of solid feed and weaning are more important determinants of gut bacterial succession in piglets than breed and nursing mother as revealed by a reciprocal cross-fostering model[J]. Environ Microbiol, 2016, 18 (5): 1566- 1577. doi: 10.1111/1462-2920.13272
11	LI F , ZHANG Z Y , BAI Y , et al. Glucosamine improves non-alcoholic fatty liver disease induced by high-fat and high-sugar diet through regulating intestinal barrier function, liver inflammation, and lipid metabolism[J]. Molecules, 2023, 28 (19): 6918. doi: 10.3390/molecules28196918
12	SHMAGEL A , DEMMER R , KNIGHTS D , et al. The effects of glucosamine and chondroitin sulfate on gut microbial composition: A systematic review of evidence from animal and human studies[J]. Nutrients, 2019, 11 (2): 294. doi: 10.3390/nu11020294
13	YU L H , LI H M , PENG Z , et al. Early weaning affects liver antioxidant function in piglets[J]. Animals (Basel), 2021, 11 (9): 2679.
14	UPADHAYA S D , KIM I H . The Impact of weaning stress on gut health and the mechanistic aspects of several feed additives contributing to improved gut health function in weanling piglets-a review[J]. Animals (Basel), 2021, 11 (8): 2418.
15	HEO J M , OPAPEJU F O , PLUSKE J R , et al. Gastrointestinal health and function in weaned pigs: a review of feeding strategies to control post-weaning diarrhoea without using in-feed antimicrobial compounds[J]. J Anim Physiol Anim Nutr (Berl), 2013, 97 (2): 207- 237. doi: 10.1111/j.1439-0396.2012.01284.x
16	田威龙, 司景磊, 刘笑笑, 等. 高脂高糖饮食对小型猪肠道微生物的影响[J]. 畜牧兽医学报, 2022, 53 (4): 1143- 1153. doi: 10.11843/j.issn.0366-6964.2022.04.014
	TIAN W L , SI J L , LIU X X , et al. Effects of high-fat and high-suger diet on intestinal microbiota in minipigs[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53 (4): 1143- 1153. doi: 10.11843/j.issn.0366-6964.2022.04.014
17	JI F J , WANG L X , YANG H S , et al. Review: The roles and functions of glutamine on intestinal health and performance of weaning pigs[J]. Animal, 2019, 13 (11): 2727- 2735. doi: 10.1017/S1751731119001800
18	GRESSE R , CHAUCHEYRAS-DURAND F , FLEURY M A , et al. Gut microbiota dysbiosis in postweaning piglets: Understanding the keys to health[J]. Trends Microbiol, 2017, 25 (10): 851- 873. doi: 10.1016/j.tim.2017.05.004
19	ZHU L H , ZHAO K L , CHEN X L , et al. Impact of weaning and an antioxidant blend on intestinal barrier function and antioxidant status in pigs[J]. J Anim Sci, 2012, 90 (8): 2581- 2589. doi: 10.2527/jas.2011-4444
20	CORINO C , PROST M , PIZZI B , et al. Dietary plant extracts improve the antioxidant reserves in weaned piglets[J]. Antioxidants(Basel), 2021, 10 (5): 702.
21	GRESSE R , CHAUCHEYRAS-DURAND F , DENIS S , et al. Weaning-associated feed deprivation stress causes microbiota disruptions in a novel mucin-containing in vitro model of the piglet colon (MPigut-IVM)[J]. J Anim Sci Biotechnol, 2021, 12 (1): 75. doi: 10.1186/s40104-021-00584-0
22	CHEN L M , XU Y S , CHEN X Y , et al. The maturing development of gut microbiota in commercial piglets during the weaning transition[J]. Front Microbiol, 2017, 8, 1688. doi: 10.3389/fmicb.2017.01688
23	胡宁敏, 陈代文, 余冰, 等. 丁酸对断奶仔猪腹泻的缓解作用及其机理研究进展[J]. 动物营养学报, 2020, 32 (5): 1973- 1979.
	HU N M , CHEN D W , YU B , et al. Research progress on relaxation effects of butyric acid on diarrhea in weaned piglets and its mechanism[J]. Chinese Journal of Animal Nutrition, 2020, 32 (5): 1973- 1979.
24	刘月帅. 妊娠期添加氨基葡萄糖对定时输精母猪繁殖性能的影响[D]. 兰州: 西北民族大学, 2023.
	LIU Y S. Effect of glucosamine on reproductive performance of gilts with timed insemination[D]. Lanzhou: Northwest University for Nationalities, 2023. (in Chinese)
25	SHEN J , ZHANG B R , WEI G F , et al. Molecular profiling of the Clostridium leptum subgroup in human fecal microflora by PCR-denaturing gradient gel electrophoresis and clone library analysis[J]. Appl Environ Microbiol, 2006, 72 (8): 5232- 5238. doi: 10.1128/AEM.00151-06
26	张德明, 黄嘉訸, 李劲树, 等. 猪肠道微生物及其代谢产物与肠道屏障研究进展[J]. 畜牧兽医学报, 2022, 53 (5): 1334- 1344. doi: 10.11843/j.issn.0366-6964.2022.05.002
	ZHANG D M , HUANG J H , LI J S , et al. Research progress of gut microbiota, metabolites and gut barrier in pigs[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53 (5): 1334- 1344. doi: 10.11843/j.issn.0366-6964.2022.05.002
27	ZHANG J , CHEN X Y , LIU P , et al. Dietary Clostridium butyricum induces a phased shift in fecal microbiota structure and increases the acetic acid-producing bacteria in a weaned piglet model[J]. J Agric Food Chem, 2018, 66 (20): 5157- 5166. doi: 10.1021/acs.jafc.8b01253
28	THOMAS F , HEHEMANN J H , REBUFFET E , et al. Environmental and gut bacteroidetes: The food connection[J]. Front Microbiol, 2011, 2, 93.
29	WANG J Y , HAN L , LIU Z Y , et al. Genus unclassified_Muribaculaceae and microbiota-derived butyrate and indole-3-propionic acid are involved in benzene-induced hematopoietic injury in mice[J]. Chemosphere, 2023, 313, 137499. doi: 10.1016/j.chemosphere.2022.137499
30	刘帅奇. 不同前处理的青蒿、常山对湖羊自然感染球虫的驱杀效果和对羊肠道菌群的影响[D]. 郑州: 河南农业大学, 2024.
	LIU S Q. The efficacy of Artemisia annua and Dichroa febrifuga on natural infection of coccidia in Hu sheep and the effect on intestinal microflora of sheep[D]. Zhengzhou: Henan Agricultural University, 2024. (in Chinese)
31	JIANG P Y , YU F F , ZHOU X , et al. Dissecting causal links between gut microbiota, inflammatory cytokines, and DLBCL: a Mendelian randomization study[J]. Blood Adv, 2024, 8 (9): 2268- 2278. doi: 10.1182/bloodadvances.2023012246
32	JIANG X Y , LU N S , ZHAO H C , et al. The Microbiome-metabolome response in the colon of piglets under the status of weaning stress[J]. Front Microbiol, 2020, 28;11, 2055.
33	GUPTA A , CHAN S Y , TOH R , et al. Gestational diabetes-related gut microbiome dysbiosis is not influenced by different Asian ethnicities and dietary interventions: a pilot study[J]. Sci Rep, 2024, 14 (1): 9855. doi: 10.1038/s41598-024-60386-y
34	MOYA A , FERRER M . Functional redundancy-induced stability of gut microbiota subjected to disturbance[J]. Trends Microbiol, 2016, 24 (5): 402- 413.
35	ZHANG Q J , GONG J T , XIANG H K , et al. Effects of main active components of rosemary on growth performance, meat quality and lipid metabolism in finishing pigs[J]. Anim Nutr, 2023, 15, 341- 349.
36	MA D D , YU M , ZHANG M H , et al. Research Note: The effect of photoperiod on the NLRP3 inflammasome and gut microbiota in broiler chickens[J]. Poult Sci, 2024, 103 (4): 103507.
37	WU Y L , LIN A H , CHEN C H , et al. Glucosamine attenuates cigarette smoke-induced lung inflammation by inhibiting ROS-sensitive inflammatory signaling[J]. Free Radic Biol Med, 2014, 69, 208- 218.
38	TARAS D , SIMMERING R , COLLINS MD , et al. Reclassification of Eubacterium formicigenerans Holdeman and Moore 1974 as Dorea formicigenerans gen. nov., comb. nov., and description of Dorea longicatena sp. nov., isolated from human faeces[J]. Int J Syst Evo Microbiol, 2002, 52 (Pt2): 423- 428.
39	ZHU LA A L T , FENG Y Q , HU D , et al. Enzymatically prepared alginate oligosaccharides improve broiler chicken growth performance by modulating the gut microbiota and growth hormone signals[J]. J Anim Sci Biotechnol, 2023, 14 (1): 96.

项目Item	含量Content
原料Ingredient
玉米Corn	53.00
大豆粕Soybean meal	20.00
膨化大豆Extruded soybean	10.60
鱼粉Fishmeal	4.00
乳清粉Driedwhey	7.50
大豆油Soybean oil	1.00
L-赖氨酸盐酸盐L-Lys·HCl	0.42
DL-蛋氨酸DL-Met	0.15
L-苏氨酸L-Thr	0.10
L-色氨酸L-Trp	0.03
磷酸氢钙CaHPO₄	1.10
石粉Limestone	0.80
食盐NaCl	0.30
预混料Premix¹⁾	1.00
合计Total	100.00
营养水平Nutrient levels²⁾
消化能/(MJ·kg^-1) DE	14.47
粗蛋白CP	20.54
钙Ca	0.82
总磷TP	0.71
赖氨酸Lys	1.50
蛋氨酸Met	0.50
苏氨酸Thr	0.92
色氨酸Trp	0.27

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氨基葡萄糖对断奶仔猪血清抗氧化、炎症指标以及肠道微生物的影响

Effects of Glucosamine on Serum Anti-oxidation, Inflammatory Indexes and Intestinal Microbes in Weaned Piglets

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