促黄体生成素受体在雌性山羊背根神经节中的表达分析

doi:10.11843/j.issn.0366-6964.2014.07.021

Abstract

Abstract:

The objective of this study was to explore whether dorsal root ganglion (DRG) have the target cells effected to luteinizing hormone (LH)，and observe the distribution of luteinizing hormone receptor(LHR) in dorsal root ganglion.Immunohistochemical SP method was adopted to detect the distribution of LHR in cervical-4，thoracic-6 and lumbar-2 DRG of female goats.Results were as follows：In cervical-4，thoracic-6 DRG，small and medium-sized neurons were strong or medium positive to LHR，while the large neurons had no staining.The distribution characteristics of LHR in small and medium-sized neurons of lumbar-2 DRG as well as to in cervical-4 and thoracic-6 DRG，but the large neurons were weak positive to LHR in lumbar DRG.Image analysis showed a significant difference of LHR expression between neurons and non-neurons in cervical-4，thoracic-6 and lumbar-2 DRG (P＜0.01).In addition，the expression of LHR among the cervical-4，thoracic-6 and lumbar-2 DRG also have significant difference (P＜0.01/0.05).The results indicate that small，medium-sized neurons in DRG were the main target cells of LH，which implies that LH may regulate the transmision of the sense to temperature，pain，touch and the sensory nerve activity associated with harmful stimulation，through the LHR distributed on small，medium-sized neurons in body-visceral sensory DRG.

CLC Number:

S852.1

DONG Wei，HUANG Shuang，XU Yong-ping，TIAN Yuan-yuan，LIU Wen-gang. Expression of Luteinizing Hormone Receptor in Cervical，Thoracic and Lumbar Dorsal Root Ganglion of Female Goat[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2014, 45(7): 1175-1181.

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Expression of Luteinizing Hormone Receptor in Cervical，Thoracic and Lumbar Dorsal Root Ganglion of Female Goat

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