生物被膜在动物细菌感染致病机理中的作用

doi:10.11843/j.issn.0366-6964.2025.01.010

Abstract

Abstract:

Bacteria biofilm refers to the bacterial aggregates formed by embedding the bacterial into the protective matrix which self produces. The survival mode based on biofilms helps microorganisms resist external threats such as immune system and drug treatments. Therefore, biofilms of bacterial organisms can exacerbate bacterial infections and lead to serious animal diseases. Biofilm plays a role in the pathogenesis of animal pathogens, including inducing and regulating local inflammatory responses and promoting intracellular invasion. The physical barrier function can provide protection for pathogens, reduce the treatment effectiveness, and increase the risk of chronic and subclinical infections. Bacteria and their biofilms can infect husbandry animals, wild animals, and companion animals. The review shows the role of biofilms in the pathogenesis of bacterial infections in animal cardiovascular, central nervous, digestive, reproductive, respiratory, urinary, and skin systems, aiming to provide reference for accurate detection and effective treatment of animal bacterial biofilms.

Key words: biofilm, bacterial, animals, chronic infection

CLC Number:

S852.61

ZHANG Lei, CHEN Liang, FENG Wanyu, LAN Shijie, MIAO Yan, TIAN Qiufeng, BAI Changsheng, ZHANG Bei, DONG Jiaqiang, JIANG Botao, WANG Hongbao, SHI Tongrui, HUANG Xuankai. The Role of Biofilms in the Pathogenesis of Animal Bacterial Infections[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(1): 107-114.

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The Role of Biofilms in the Pathogenesis of Animal Bacterial Infections

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