FecB基因在绵羊繁殖性能上的研究进展

doi:10.11843/j.issn.0366-6964.2023.04.003

Abstract

Abstract: The reproductive performance of sheep is a very important economic trait. The number of lambs is directly related to the number of ovulation each time, and the growth and development of ovum is influenced by the interaction of ovarian endocrine and paracrine. FecB gene is the first multifetal major gene discovered in sheep. The BMP signaling pathway in the ovary of sheep carrying this gene is damaged and the activity is reduced, and some members of TGF-β family are inactivated, which inhibits the proliferation of GCs and improves the sensitivity of FSH, effectively improves ovulation rate and lambing rate of sheep, which is conducive to expanding the breeding scale and improving economic benefits. In this paper, the discovery of FecB gene, its action mechanism, its effect on follicular development, reproductive ability and offspring growth and development, as well as its application in breeding were reviewed, in order to provide reference for the mechanism research and breeding work of improving sheep reproductive performance.

Key words: sheep, FecB, reproductive performance

CLC Number:

S826.3

YANG Chulei, ZHANG Yiyuan, TANG Hong, GUO Yanhua, REN Xiumeiao, WANG Limin, ZHOU Ping. Research Progress of FecB Gene on Reproductive Performance of Sheep[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(4): 1370-1380.

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Research Progress of FecB Gene on Reproductive Performance of Sheep

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