中国2012—2022年羊群中蓝舌病毒流行的Meta分析

doi:10.11843/j.issn.0366-6964.2024.02.028

Abstract

Abstract: The aim of this research was to systematically evaluate and analyze the infection status of bluetongue virus (BTV) in sheep flocks in China from 2012 to 2022, and to provide evidence for the prevention and control of BTV in sheep flocks in China. A Meta-analysis was conducted after searching the databases of CNKI, Wanfang, VIP, PubMed and ScienceDirect for articles on the sheep BTV prevalence in China published from 2012 to 2022. After searching and screening, a total of 28 studies were brought into the Meta-analysis, including 38 226 sheep of which 9 109 sheep were BTV positive. The overall prevalence of BTV was 23.8% (95%CI: 23.4,24.3) in sheep and goats, 29.4% (95%CI: 14.7,44.1) in sheep and 25.1% (95%CI: 18.6,31.7) in goats. Among provinces/cities in China, the prevalence was highest in Chongqing 34.6% (95%CI: 32.0,37.1), followed by Yunnan province and Inner Mongolia Autonomous Region. Subgroup analysis showed that there were significant regional differences in the prevalence of BTV (P=0.011). The prevalence of BTV in eastern, southern, western, northern and central areas of China were 6.1% (95%CI: 4.3,7.9), 33.8% (95%CI: 29.5,38.1) and 21.7% (95%CI: 17.1,26.2), 21.0% (95%CI: 8.3,33.6) and 26.6% (95%CI: 24.3,28.8), respectively. At the same time, detection methods and climate types were also risk factors for BTV prevalence in sheep in China(P<0.05). The results showed that the prevalence of BTV was high and the distribution was wide among sheep in China. It is necessary to continue the surveillance and prevention of BTV infection in China.

Key words: bluetongue virus, bluetongue, sheep, prevalence rate, Meta-analysis

CLC Number:

S851.3

GAO Hui, FANG Min, JIANG Lingling, MA Yaoyu, LIU Qiang, ZHANG Gang, NIU Xiaoxia, WANG Pu, LI Yong, ZHANG Sinong. Meta-analysis of Bluetongue Virus Prevalence in Sheep Flocks in China from 2012—2022[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(2): 706-717.

References

[1] CHAND S,CHAND K,BISWAS S K,et al.Development of a rapid lateral flow immunochromatography assay for the detection of group-specific antibodies against VP7 protein of bluetongue virus in multiple species[J].J Immunol Methods,2021,499:113166.
[2] NAJARNEZHAD V,RAJAE M.Seroepidemiology of bluetongue disease in small ruminants of north-east of Iran[J].Asian Pac J Trop Biomed,2013,3(6):492-495.
[3] 易华山,赵瑶,马鲜平,等.蓝舌病毒结构与组装机制研究进展[J].家畜生态学报,2020,41(7):79-84.
YI H S,ZHAO Y,MA X P,et al.Advance in structure and assembly mechanism of bluetongue virus[J].Acta Ecologae Animalis Domastici,2020,41(7):79-84.(in Chinese)
[4] ZIENTARA S,SAILLEAU C,VIAROUGE C,et al.Novel bluetongue virus in goats,Corsica,France,2014[J].Emerg Infect Dis,2014,20(12):2123-2125.
[5] 李书宁,邓恩诚,蔡纪芬,等.2017年云南西双版纳蓝舌病血清流行病学调查[J].上海畜牧兽医通讯,2018(4):34-35.
LI S N,DENG E C,CAI J F,et al.Seroepidemiological survey of bluetongue disease in Xishuangbanna,Yunnan Province in 2017[J].Shanghai Journal of Animal Husbandry and Veterinary Medicine,2018(4):34-35.(in Chinese)
[6] BELBIS G,ZIENTARA S,BRÉARD E,et al.Bluetongue virus:from BTV-1 to BTV-27[J].Adv Virus Res,2017,99:161-197.
[7] 叶升,陈月红,谢其冰.单个发生率为0或1的meta分析及软件实现[J].中国卫生统计,2022,39(2):316-320.
YE S,CHEN Y H,XIE Q B.Meta-analysis and software implementation with single incidence of 0 or 1[J].Chinese Journal of Health Statistics,2022,39(2):316-320.(in Chinese)
[8] 林俊.广西反刍动物蓝舌病血清学调查及病原分离鉴定[D].南宁:广西大学,2012.
LIN J.Serology survey and isolation and identification of bluetongue virus in ruminants of Guangxi[D].Nanning:Guangxi University,2012.(in Chinese)
[9] 王慧,覃岚,尹鑫,等.2012年贵州羊蓝舌病血清流行病学调查及影响因素分析[J].中国动物检疫,2013,30(11):52-56.
WANG H,QIN L,YIN X,et al.The serological survey and influencing factors analysis of sheep bluetongue in Guizhou Province in 2012[J].China Animal Health Inspection,2013,30(11):52-56.(in Chinese)
[10] 毛黎红,王开功,周碧君,等.贵州省牛羊口蹄疫、蓝舌病血清流行病学调查[C]//中国畜牧兽医学会2013年学术年会论文集.北京:中国畜牧兽医学会,2013:293-293.
MAO L H,WANG K G,ZHOU B J,et al.Seroepidemiological survey of foot-and-mouth disease and bluetongue disease in cattle and sheep in Guizhou province[C]//Proceedings of the China Animal Husbandry and Veterinary Society 2013 Academic Annual Meeting.Beijing:Chinese Association of Animal Science and Veterinary Medicine,2013:293-293.(in Chinese)
[11] 王玉,谷文喜,石保新,等.2012年新疆蓝舌病血清学调查及区间分布[J].中国动物检疫,2014,31(5):52-55.
WANG Y,GU W X,SHI B X,et al.Serological survey and analysis of bluetongue in Xingjian area in 2012[J].China Animal Health Inspection,2014,31(5):52-55.(in Chinese)
[12] 毛立,李文良,杨蕾蕾,等.江苏省部分地区牛羊蓝舌病血清学调查及监控[J].西南农业学报,2015,28(6):2784-2787.
MAO L,LI W L,YANG L L,et al.Serological survey and monitor of bluetongue virus (BTV) infections in ruminants in Jiangsu province[J].Southwest China Journal of Agricultural Sciences,2015,28(6):2784-2787.(in Chinese)
[13] 吕敏娜,林丽琴,陈琴苓,等.广东地区蓝舌病流行病学初步研究[J].中国预防兽医学报,2015,37(7):499-501.
LV M N,LIN L Q,CHEN Q L,et al.A preliminary study of the epidemiology of bluetongue disease in Guangdong[J].Chinese Journal of Preventive Veterinary Medicine,2015,37(7):499-501.(in Chinese)
[14] 何雪峰,刘君,刘江,等.毕节市牛、羊血清的流行病学调查报告[J].中国畜禽种业,2015(5):8-9.
HE X F,LIU J,LIU J,et al.Epidemiological investigation of serum of cattle and sheep in Bijie City[J].The Chinese Livestock and Poultry Breeding,2015(5):8-9.(in Chinese)
[15] 张胜男.内蒙古蓝舌病与鹿流行性出血热流行病学调查及相关虫媒鉴定[D].呼和浩特:内蒙古农业大学,2016.
ZHANG S N.The serological survey of bluetongue and epizootic haemorrhage disease and insect-borne identification in Inner Mongolia[D].Hohhot:Inner Mongolia Agricultural University,2016.(in Chinese)
[16] 张明国,安燕.攀西地区牛羊蓝舌病血清学调查[J].上海畜牧兽医通讯,2016(5):39-40,43.
ZHANG M G,AN Y.Serological investigation of bluetongue disease in cattle and sheep in Panxi area[J].Shanghai Journal of Animal Husbandry and Veterinary Medicine,2016(5):39-40,43.(in Chinese)
[17] 邢崔昱.湖北山羊蓝舌病血清学调查及病原分离与鉴定[D].晋中:山西农业大学,2016.
XING C Y.Serology survey and isolation and identification of goat bluetongue virus in Hubei[D].Jinzhong:Shanxi Agricultural University,2016.(in Chinese)
[18] 曲久,高家登.西藏那曲地区蓝舌病血清流行病学调查[J].中国动物检疫,2016,33(2):15-16.
QU J,GAO J D.Sero-epidemiological survey of bluetongue in Naqu prefecture[J].China Animal Health Inspection,2016,33(2):15-16.(in Chinese)
[19] 韩明浩.内蒙古地区2015年牛羊蓝舌病流行病学调查及病毒的初步分离鉴定[D].呼和浩特:内蒙古农业大学,2016.
HAN M H.The epidemiological investigation of bluetongue infected cattles and sheep in Inner Mongolian areas in 2015 and the preliminary separation and identification of pathogeny[D].Hohhot:Inner Mongolia Agricultural University,2016.(in Chinese)
[20] 段正赢,戴德强,周丹娜,等.2013年湖北省山羊蓝舌病血清学调查[J].畜牧与兽医,2016,48(2):110-112.
DUAN Z Y,DAI D Q,ZHOU D N,et al.Serological survey of goat bluetongue in Hubei Province in 2013[J].Animal Husbandry & Veterinary Medicine,2016,48(2):110-112.(in Chinese)
[21] 陈建闪,申杜娟,于叶平,等.山西省牛羊蓝舌病血清流行病学调查与分析[J].中国动物检疫,2016,33(9):16-19.
CHEN J S,SHEN D J,YU Y P,et al.The seroepidemiology survey and analysis on bluetongue of cattle and sheep in Shanxi Province[J].China Animal Health Inspection,2016,33(9):16-19.(in Chinese)
[22] XU Q Y,SUN E C,FENG Y F,et al.Development of a novel protein chip for the detection of bluetongue virus in China[J].J Virol Methods,2016,234:28-33.
[23] 冯杰,崔燕,余四九,等.贵州高海拔山区羊疫病血清学调查[J].贵州农业科学,2016,44(6):103-107.
FENG J,CUI Y,YU S J,et al.Serological test of main goat epidemic diseases in high-elevation mountainous area in Guizhou[J].Guizhou Agricultural Sciences,2016,44(6):103-107.(in Chinese)
[24] 徐茂文,李涛,张元鑫,等.贵州省山羊疫病现状与防控措施调查分析[J].畜牧与兽医,2016,48(1):93-96.
XU M W,LI T,ZHANG Y X,et al.Investigation on the current status and control measures of goat disease in Guizhou Province[J].Animal Husbandry & Veterinary Medicine,2016,48(1):93-96.(in Chinese)
[25] 袁媛,李前勇,张德志,等.渝西地区牛羊蓝舌病的血清学调查[J].中国兽医杂志,2017,53(9):42-44.
YUAN Y,LI Q Y,ZHANG D Z,et al.Serological investigation of bluetongue disease in cattle and sheep in west Chongqing area[J].Chinese Journal of Veterinary Medicine,2017,53(9):42-44.(in Chinese)
[26] 舒展,刘帅,加帕尔·哈斯木,等.新疆地区羊蓝舌病流行病学调查与分析[J].草食家畜,2017(1):47-51.
SHU Z,LIU S,JIAPAER H,et al.Epidemiological investigation and analysis of sheep bluetongue in Xinjiang[J].Grass-Feeding Livestock,2017(1):47-51.(in Chinese)
[27] 韦玉韩,冷吉树,黄永红,等.富宁县蓝舌病血清学调查[J].云南畜牧兽医,2017(3):32-33.
WEI Y H,LENG J S,HUANG Y H,et al.Serological investigation of bluetongue disease in Funing County[J].Yunnan Journal of Animal Science and Veterinary Medicine,2017(3):32-33.(in Chinese)
[28] 杨蕾蕾,李文良,毛立,等.2014~2016年江苏省部分地区及监控点山羊的蓝舌病血清学调查[J].江西农业学报,2018,30(2):76-79.
YANG L L,LI W L,MAO L,et al.Serological survey and monitoring of bluetongue virus (BTV) infections in goats in several areas of Jiangsu province from 2014 to 2016[J].Acta Agriculturae Jiangxi,2018,30(2):76-79.(in Chinese)
[29] MA J,GAO X,LIU B Y,et al.Spatial patterns and risk factors of bluetongue virus infection in Inner Mongolia,China[J].Vector Borne Zoonotic Dis,2019,19(7):525-532.
[30] MA J,GAO X,LIU B Y,et al.Epidemiology and spatial distribution of bluetongue virus in Xinjiang,China[J].PeerJ,2019,7:e6514.
[31] 王芳,肖雷,朱沛,等.2018年我国蓝舌病血清学调查及影响因素分析[J].云南畜牧兽医,2019(5):1-3.
WANG F,XIAO L,ZHU P,et al.Serological investigation and analysis of influencing factors of bluetongue disease in China in 2018[J].Yunnan Journal of Animal Science and Veterinary Medicine,2019(5):1-3.(in Chinese)
[32] 宋爱军,李军燕,罗晓平,等.内蒙古部分地区蓝舌病流行病学调查[J].当代畜禽养殖业,2019(12):54,52.
SONG A J,LI J Y,LUO X P,et al.Epidemiological survey of bluetongue disease in some areas of Inner Mongolia[J].Modern Animal Husbandry,2019(12):54,52.(in Chinese)
[33] 郑华,张素辉.山羊蓝舌病血清学调查[J].今日畜牧兽医,2019,35(12):12.
ZHENG H,ZHANG S H.Serological investigation of bluetongue disease in goat[J].Today Animal Husbandry and Veterinary Medicine,2019,35(12):12.(in Chinese)
[34] 朱沛,肖雷,苗海生,等.我国牛羊蓝舌病血清学调查[J].中国兽医杂志,2020,56(7):10-14.
ZHU P,XIAO L,MIAO H S,et al.Large-scale serological survey of bluetongue in China[J].Chinese Journal of Veterinary Medicine,2020,56(7):10-14.(in Chinese)
[35] CARPENTER S,GROSCHUP M H,GARROS C,et al.Culicoides biting midges,arboviruses and public health in Europe[J].Antiviral Res,2013,100(1):102-113.
[36] 李茂林,张七斤,徐青元.蓝舌病在全球的分布概况[J].畜牧兽医学报,2021,52(4):881-890.
LI M L,ZHANG Q J,XU Q Y.Global distribution of bluetongue[J].Acta Veterinaria et Zootechnica Sinica,2021,52(4):881-890.(in Chinese)
[37] WILSON A J,MELLOR P S.Bluetongue in Europe:past,present and future[J].Philos Trans Roy Soc B:Biol Sci,2009,364(1530):2669-2681.
[38] PURSE B V,MELLOR P S,ROGERS D J,et al.Climate change and the recent emergence of bluetongue in Europe[J].Nat Rev Microbiol,2005,3(2):171-181.
[39] SCHULZ C,BRÉARD E,SAILLEAU C,et al.Bluetongue virus serotype 27:detection and characterization of two novel variants in Corsica,France[J].J Gen Virol,2016,97(9):2073-2083.
[40] SZMARAGD C,GUNN G J,GUBBINS S.Assessing the consequences of an incursion of a vector-borne[LL]disease.II.Spread of bluetongue in Scotland and impact of vaccination[J].Epidemics,2010,2(3):139-147.
[41] QIN S M,LIN J,LI L,et al.Seroprevalence and potential risk factors of bluetongue virus infection in domestic cattle and goats in Guangxi,Southern China[J].Vector Borne Zoonotic Dis,2020,20(7):551-556.
[42] JIMÉNEZ-CABELLO L,UTRILLA-TRIGO S,CALVO-PINILLA E,et al.Viral vector vaccines against bluetongue virus[J].Microorganisms,2020,9(1):42.
[43] BENELLI G,BUTTAZZONI L,CANALE A,et al.Bluetongue outbreaks:looking for effective control strategies against Culicoides vectors[J].Res Vet Sci,2017,115:263-270.
[44] 郑可人.我国蓝舌病传播媒介风险因素分析及适生范围扩展趋势研究[D].哈尔滨:东北农业大学,2020.
ZHENG K R.Study on risk factor analysis and suitable range expansion trend of bluetongue vector in China[D].Harbin:Northeast Agricultural University,2020.(in Chinese)
[45] CHANDA M M,CARPENTER S,PRASAD G,et al.Livestock host composition rather than land use or climate explains spatial patterns in bluetongue disease in South India[J].Sci Rep,2019,9(1):4229.
[46] NICOLAS G,TISSEUIL C,CONTE A,et al.Environmental heterogeneity and variations in the velocity of bluetongue virus spread in six European epidemics[J].Prev Vet Med,2018,149:1-9.
[47] KOUMBATI M,MANGANA O,NOMIKOU K,et al.Duration of bluetongue viraemia and serological responses in experimentally infected European breeds of sheep and goats[J].Vet Microbiol,1999,64(4):277-285.
[48] 苗海生,李乐,廖德芳,等.蓝舌病多克隆抗体C-ELISA检测方法的建立和比较研究[J].云南农业大学学报,2014,29(1):58-62.
MIAO H S,LI L,LIAO D F,et al.Research on establishment and comparison of blue-tongue-virus multi-clone antibody C-ELISA[J].Journal of Yunnan Agricultural University,2014,29(1):58-62.(in Chinese)
[49] LIU F,GONG Q L,ZHANG R,et al.Prevalence and risk factors of bluetongue virus infection in sheep and goats in China:a systematic review and meta-analysis[J].Microb Pathog,2021,161:105170.

Meta-analysis of Bluetongue Virus Prevalence in Sheep Flocks in China from 2012—2022

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