猪基因组结构变异研究进展

doi:10.11843/j.issn.0366-6964.2022.09.002

Abstract

Abstract: Structural variation (SV) is widely distributed in the genome and mainly occurs in the form of deletion, insertion, duplication, inversion and translocation. SV can affect the gene dosage directly or indirectly through different mechanisms, thereby causing phenotypic variation and even disease in livestock and poultry. With the development of molecular biology and the advancement of new genomic technologies, SV has been increasingly studied in the pig genome, including reproductive traits, meat quality traits, growth traits, coat color, diseases, etc. In this paper, the definition, classification, formation mechanism, detection method and research status of SV for pig genomes were reviewed based on relevant research reports from home and abroad. The problems existing in the SV research were suggested and the future research trends were prospected.

Key words: structural variation (SV), pig, genome, traits

CLC Number:

S828.2

ZONG Wencheng, WANG Ligang, SONG Chengyi, WANG Lixian, ZHANG Longchao. Advances of Structural Variation in Pig Genome[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(9): 2833-2844.

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Advances of Structural Variation in Pig Genome

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