拷贝数变异在家禽育种中的研究进展

doi:10.11843/j.issn.0366-6964.2020.11.003

Abstract

Abstract: Copy number variation (CNV) is an important type of genetic variation which widely exists in livestock and poultry genomes. It usually occurs in the form of deletion or duplication of large DNA sequences, which directly affects gene expression and function. CNV is closely related to many genetic diseases and phenotypic traits, and therefore has attracted close attention of animal genetics and breeding workers. The formation causes, action mechanism, detection methods, and the research progress of CNV in poultry were summarized in this article, and the difficulties and problems in current CNV studies were discussed, which aims to provide a reference for the realization of CNV as a molecular genetic marker in poultry for assisted breeding.

Key words: copy number variation, genome, poultry breeding

CLC Number:

S813.1

ZHANG Yi, BAI Hao, BI Yulin, LU Ao, HUANG Yanli, CHEN Guohong, CHANG Guobin. Research Progress of Copy Number Variation in Poultry Breeding[J]. Acta Veterinaria et Zootechnica Sinica, 2020, 51(11): 2633-2640.

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Research Progress of Copy Number Variation in Poultry Breeding

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