华西牛胴体及原始分割肉块重量性状遗传参数估计与全基因组关联分析

doi:10.11843/j.issn.0366-6964.2023.09.008

Abstract

Abstract: This study aimed to estimate the genetic parameters for carcass and primal cuts weight traits and excavate the related candidate genes in Huaxi cattle by using genomic information. In this study, 17 carcass traits and primal cuts weight traits from 1 585 18-months-old slaughter Huaxi cattle were selected as the research subjects, the R program, GCTA software and 770K high density chip data were utilized to estimate the genetic parameters and excavate the related candidate genes for these 17 traits. The results showed that the primal cuts weight in extremities and hip area were high heritability traits (0.41-0.57), while the primal cuts weight in trunk, marketing weight, carcass weight, dressing percentage and meat percentage were medium heritability traits (0.19-0.39). Ultimately, 26 significant SNPs were detected by genome-wide association study and 24 candidate genes were located. Enrichment analysis showed these candidate genes were associated with the cell proliferation, lipid metabolism, cellular energy conversion, etc. NSMF, NOXA, TEFM, MATN1, MKX, FOXO1 were the promising candidate genes for muscle growth in Huaxi cattle. These results might provide reference for the optimization of the subsequent breeding program of Huaxi cattle.

Key words: Huaxi cattle, carcass trait, primal cuts weight trait, genetic parameter, genome-wide association study

CLC Number:

S823.2

LI Keanning, DU Lili, AN Bingxing, DENG Tianyu, LIANG Mang, CAO Sheng, DU Yueying, XU Lingyang, GAO Xue, ZHANG Lupei, LI Junya, GAO Huijiang. Genetic Parameter Estimation and Genome-Wide Association Study for Carcass Traits and Primal Cuts Weight Traits in Huaxi Cattle[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(9): 3664-3676.

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Genetic Parameter Estimation and Genome-Wide Association Study for Carcass Traits and Primal Cuts Weight Traits in Huaxi Cattle

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