囊膜糖蛋白gE对α疱疹病毒毒力的影响

doi:10.11843/j.issn.0366-6964.2020.07.004

Abstract

Abstract: In recent years, new progress has been made in the research of glycoprotein gE of alphaherpesvirus in virus intercellular transmission, nervous system infection, and immune evasion. gE is involved in syncytium formation, anterograde and retrograde neurotransmission, and is also the first reported viral protein that inhibits the activation of plasmacytoid dendritic cells to produce type I interferon. This summary reviews the relationship between gE and virulence to provide useful information for the further study of gE.

Key words: alphaherpesvirus, glycoprotein E, virulence, immune escape, neurovirulence

CLC Number:

S852.659.1

HUANG Yalin, CHENG Anchun, WANG Mingshu. Effect of Alphaherpesvirus Glycoprotein gE on Virulence[J]. Acta Veterinaria et Zootechnica Sinica, 2020, 51(7): 1506-1514.

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Effect of Alphaherpesvirus Glycoprotein gE on Virulence

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