Acta Veterinaria et Zootechnica Sinica ›› 2023, Vol. 54 ›› Issue (12): 4934-4942.doi: 10.11843/j.issn.0366-6964.2023.12.005

• REVIEW • Previous Articles     Next Articles

Research Progress on the Virulence Factors of Avibacterium paragallinarum

ZHI Yan1, MEI Chen2, LIU Zhenyi1, WUYUN Gerile3, WANG Hongjun2*, HU Ge1*   

  1. 1. College of Animal Science and Technology, Beijing University of Agriculture, Beijing 102206, China;
    2. Institute of Animal Husbandry and Veterinary Medicine, Beijing Municipal Academy of Agriculture and Forestry Science, Beijing 100097, China;
    3. Zhalute Banner Livestock Breeding Center, Tongliao 029100, China
  • Received:2023-03-21 Online:2023-12-23 Published:2023-12-26

Abstract: Avibacterium paragallinarum (Apg) is the pathogen of infectious coryza in chickens. It induces symptoms such as nasal cavity mucus secretion, sneezing, infraorbital sinus swelling, facial edema, and conjunctivitis. These clinical manifestations lead to stunted growth and a significant decrease in egg production, posing a threat to poultry farming. The pathogenicity of Apg is influenced by various factors, including cell wall structural components like capsule and lipopolysaccharide, as well as functional proteins secreted by the cell such as hemagglutinin and metalloproteinases. This paper provides a review of the research progress on the virulence factors of Apg, focusing on the biofilm system, secretory system, and bacterial iron capture system. The aim is to offer a theoretical reference for the scientific prevention and treatment of infectious coryza in chickens.

Key words: Avibacterium paragallinarum, virulence factor, infectious coryza

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