支持细胞对精原干细胞增殖、分化调控的研究进展

doi:10.11843/j.issn.0366-6964.2019.02.003

Abstract

Abstract:

The spermatogenesis of mammals is regulated by Sertoli cells (SCs), which not only provide physical support and stable microenvironment to the spermatogenesis, but also regulate and control the proliferation, differentiation, apoptosis, phagocytosis and immune privilege of generative cells through the secretion of multiple proteins. However,the exact mechanism of SCs regulating spermatogenesis in physiological situations is unclear. Therefore, in this paper, the SCs and spermatogonial stem cells (SSCs) and a series of sperm cells special structure relationship and the regulation between the two were summarized, in order to promote the in-depth study of the regulatory mechanism between the two and to provide reference for improving the animal breeding efficiency.

CLC Number:

S814

WANG Shuocheng, CHEN Xiaoli, ZHANG Linbo, WANG Dong. The Progress of the Study on the Regulation of the Proliferation, Differentiation of Spermatogonial Stem Cells by the Sertoli Cells[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2019, 50(2): 253-260.

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The Progress of the Study on the Regulation of the Proliferation, Differentiation of Spermatogonial Stem Cells by the Sertoli Cells

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