Abstract: Pluripotent stem cells (PSC) refer to cells with unlimited proliferation capacity and can differentiate to produce various tissue cells of three germ layers. They have wide application prospects in biological medicine, animal breeding and other fields. Livestock stem cells can be used to accelerate the process of breeding, generate models for biomedical research instead of mice, and produce cultured meat, etc. However, due to the interspecies differences between livestock and humans or mice, the progress of livestock pluripotent stem cell establishment is relatively lagging. At present, stable porcine PSC lines have been successfully established, while PSC lines of other livestock such as bovine, sheep, goat and horse still remain insufficient. In this review, the progress made in embryonic stem cells and induced pluripotent stem cells established in domestic animals wene summerized, as well as an outlook on the future applications of pluripotent stem cells in stem cell basis, livestock breeding and reproduction, biomedical science, and food industry was given.

Key words: livestock, embryonic stem cells, induced pluripotent stem cells, livestock breeding and reproduction, biomedical science, food industry