鸭源鸡杆菌整合子及其与耐药性的相关性分析

doi:doi: 10.11843/j.issn.0366-6964.2016.08.019

Abstract

Abstract:

The aim of the present study was to confirm existence of the integrons in Gallibacterium anatis（G.anatis）isolates and the role of integrons in multidrug resistance.The integrons class 1，2 and 3 in G.anatis isolates were detected by PCR amplification for the first time.The sensitivity of 61 G.anatis strains was tested against 13 kinds of antibiotics by Kirby-Bauer method.The correlation between multidrug resistance and integrons was analyzed.The results showed that drug resistance rates of all G.anatis isolates to clindamycin，norfloxacin and streptomycin were above 88.52%.No less than three kinds of drugs were resisted for 19 G.anatis strains which carrying class 1 integron.Among strains resisting more than five kinds of drugs，the proportion of the class 1 integron positive (78.95%) was significantly higher than that（28.57%）of class 1 integron negative strains（P＜0.01）.It was the first time，to our knowledge，that the distribution of intergons in G.anatis had been investigated. Only class 1 integron was found and multidrug resistance was very common in G.anatis isolates in this study.Class 1 integron might play an important role in the formation of multiple drug resistance phenotype of G.anatis strains.

CLC Number:

S852.612

PENG Zhi-feng，GAO Dong-sheng，LIU Hong-ying，YANG Xia，ZHAO Jun，WANG Xin-wei，LI Yong-tao，CHEN Lu，CHANG Hong-tao，WANG Chuan-qing. Gallibacterium anatis Integron and Its Correlation with the Drug Resistance[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(8): 1676-1681.

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Gallibacterium anatis Integron and Its Correlation with the Drug Resistance

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