猪丁型冠状病毒编码蛋白结构与功能研究进展

doi:10.11843/j.issn.0366-6964.2025.08.012

Abstract

Abstract:

Porcine deltacoronavirus (PDCoV) is a novel porcine enteropathogenic coronavirus that causes watery diarrhea, vomiting, and dehydrating death in lactating piglets, resulting in significant economic losses to the swine industry. The development of effective vaccines and drugs has become an important strategy to prevent and control the PDCoV. The PDCoV genome encodes several types of proteins that play important roles in viral replication and host antiviral immunity, and the study of the proteins encoded by PDCoV is conducive to revealing the mechanism of viral invasion into the host. In this paper, the structural characteristics and specific functions of structural proteins, nonstructural proteins and accessory proteins encoded by PDCoV are summarized based on the latest literature advances at home and abroad, so as to provide reference for the development of anticoronaviral drugs and vaccines.

Key words: porcine deltacoronavirus, encoded proteins, molecular mechanism, antiviral drugs

CLC Number:

S852.659.6

TAO Lihan, LIN Cui, WU Chengcheng, KANG Zhaofeng, HUANG Jianzhen. Research Progress on the Structure and Function of Proteins Encoded by Porcine Deltacoronavirus[J]. Acta Veterinaria et Zootechnica Sinica, 2025, 56(8): 3678-3689.

Figures/Tables 5

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Research Progress on the Structure and Function of Proteins Encoded by Porcine Deltacoronavirus

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