Table 1

Classification of ovarian tumors in dogs"

Fig. 1

Papillary adenomas of the ovary A. The boundaries between the papillary adenoma of the ovary and the surrounding normal ovarian tissue are well defined (arrow), and a distinct envelope is visible around the tumor (100×); B. Under high magnification, the mass is seen to consist of arboriform papillae projecting into the lumen of cystic cavities, and the tumor cells are arranged on dendritic trabeculae (arrows) (400×)"

Fig. 2

Papillary carcinoma of the ovary A. Fibrovascular tissue is seen in luteal cysts (100×); B. Well-vascularized glandular luteal cells (400×); C. Papillary carcinoma of the ovary with ill-defined borders and ruptured cystic cavity, and tumor tissue is visible as arboriform papillae (arrow) (100×); D. Tumor cells irregularly arranged on trabeculae with irregularly sized nucleus (arrow) (400×)"

Fig. 3

Rete adenoma of the ovary A. A large number of hyperplastic glandular duct-like structures are seen within rete adenoma of the ovary, and the mass is well demarcated from the surrounding area (arrow) (100×); B. Fibrous connective tissue hyperplasia within the tumor, with glandular duct-like structures in an island-like distribution (400×)"

Fig. 4

Cystadenoma of the rete ovarii A. Cysts wall consists of a single or multiple layers of epithelium, which is seen as characteristic of an adenoma (arrow), and large cystic cavities containing proteinaceous material are seen (100×); B. Tumor tissue similar to adenoma, visible as epithelial cells arranged within arboriform papillae (400×)"

Fig. 5

Cystic granulosa cell tumor of the ovary A. Part of the cystic wall of ovarian granulosa cell tumor is seen surrounding tumor cells arranged in a circular cavity (arrow) (100×); B. Cell clusters containing eosinophilic material (400×); C. Tumor cells are arranged in sheets (100×); D. Tumor cells form wreath-like radially arranged clusters of cells around small circular cavities (Call-Exner bodies) (arrow) (400×)"

Fig. 6

Histological features and immunohistochemical staining results of ovarian granulosa cell tumor A. Tumor cells are seen to form Call-Exner vesicles in ovarian granulosa cell tumors (400×); B. In ovarian granulosa cell tumors, tumor cells do not express CK7 (400×); C. In ovarian granulosa cell tumors, tumor cells express inhibin-α (400×); D. In ovarian granulosa cell tumors, tumor cells express vimentin (400×)"

Fig. 7

Ovarian supporting cell tumor A. Ovarian supporting cell tumor associated with a cyst with proteinaceous material visible in the cystic cavity (100×); B. Neutrophilic infiltration is seen locally (400×); C. Tumor cells are arranged in bundles in the mesenchyme with abundant stromal tissue (100×); D. Tumor cells are shaped like support cells and are arranged in bundles (400×)"

Fig. 8

Thecoma of the ovary A. A large mass is seen in the ovary with a clear boundary between the mass and normal tissue (100×); B. Tumor cells of thecoma are similarly spindle shaped and vacuolated, often embedded in a dense stroma (400×)"

Fig. 9

Luteoma A. Proliferating corpus luteum cells in lamellar or clumped distribution, with overall eosinophilic powdery staining of the mass (100×); B. Lipid vacuoles (arrow) are visible in the cytoplasm of granular luteal cells, and cells have a large volume (400×)"

Fig. 10

Incidence of various types of ovarian tumors in dogs, 2013-2023"

Table 2

Correlation between age and types of ovarian tumors in dogs from 2013-2023"

Table 3

Correlation between breed and types of ovarian tumors in dogs from 2013-2023"