奶牛早期妊娠免疫调控机制的研究进展

doi:10.11843/j.issn.0366-6964.2024.12.006

Abstract

Abstract:

The immune response of dairy cows is one of the key factors influencing early pregnancy embryonic loss. The establishment of pregnancy and placental development rely on the coordinated actions of immune cells (such as Tregs, macrophages, and NK cells) and immune regulatory factors, which regulate the uterine receptivity to the embryo, embryo implantation, and maternal immune tolerance. Thus, a comprehensive understanding of the immune response processes at various stages of early pregnancy in cows is essential for improving pregnancy success rates. This paper provides a detailed analysis of the immune regulation mechanisms during artificial insemination and early pregnancy in cows. It examines the balance and complex dynamic regulation between pro-inflammatory and anti-inflammatory factors in the maternal system.This research offer theoretical support for ensuring successful pregnancy through key stages including fertilization, blastocyst hatching, pregnancy recognition, and embryo implantation, aiming to enhance reproductive efficiency in dairy cows.

Key words: cow, fertilization, blastocyst hatching, pregnancy recognition, peri-implantation period

CLC Number:

S823.91

ZHENG Hao, SUN Guohan, FU Yu, YANG Zhuo, TAO Jinzhong. Research Progress on Immune Regulatory Mechanisms of Early Pregnancy in Dairy Cows[J]. Acta Veterinaria et Zootechnica Sinica, 2024, 55(12): 5391-5397.

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Research Progress on Immune Regulatory Mechanisms of Early Pregnancy in Dairy Cows

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