Acta Veterinaria et Zootechnica Sinica ›› 2024, Vol. 55 ›› Issue (12): 5368-5378.doi: 10.11843/j.issn.0366-6964.2024.12.004

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Research Progress in the Effect of Oxidative Stress on Uterus and Pregnancy in Female Livestock

MENG Yaxuan1,2,3(), LIU Yan2,3, WEI Xingru4, CHEN Guoshun1,*(), FENG Tao1,2,3,*()   

  1. 1. College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China
    2. Institute of Animal Husbandry and Veterinary Medicine (IAHVM), Beijing Academy of Agriculture and Forestry Sciences (BAAFS), Beijing 100097, China
    3. Joint Laboratory of Animal Science between IAHVM of BAAFS and Division of Agricultural Science and Natural Resource of Oklahoma State University, Beijing 100097, China
    4. Beijing Feed Industry Association, Beijing 100107, China
  • Received:2024-05-20 Online:2024-12-23 Published:2024-12-27
  • Contact: CHEN Guoshun, FENG Tao E-mail:18793606358@163.com;chengs@gsau.edu.cn;fengtao@baafs.net.cn

Abstract:

Oxidative stress is a state of excessive reactive oxygen species produced by changes of intracellular and extracellular environment, which plays an important role in the regulation of uterine function. In recent years, studies have shown that oxidative stress can regulate the function of the uterus by affecting reproductive hormones, immune responses, regulating uterine environment and cell signaling. In addition, excessive oxidative stress can impair maternal and placental function, closely related to reproductive diseases such as endometrial carcinoma, pre-eclampsia, gestational diabetes mellitus, and intrauterine growth retardation. This paper reviewed the research progress on the regulation of oxidative stress on the uterine function of female livestock in recent years, in order to better understanding the effect of oxidative stress on the uterine function of female animals, providing new theoretical guidance and practical application for improving the reproduction efficiency of female livestock.

Key words: oxidative stress, female livestock, uterus, hormone, inflammation, reproductive disease

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