反刍动物胃肠道上皮屏障功能及与微生物互作研究

doi:10.11843/j.issn.0366-6964.2023.05.004

Abstract

Abstract: The gastrointestinal tract of animals is the part which directly contacts the external environment and is always exposed to various exogenous and endogenous substances. Hence, there are functional epithelial barriers in the gastrointestinal tract to prevent various substances from invading the tissue. Gastrointestinal microbes play an important role in maintaining the homeostasis and strengthening of the gastrointestinal epithelial barrier. The gastrointestinal epithelial barrier interacts with microorganisms to regulate the growth, development, metabolism and immune function of the host gastrointestinal tract, and the establishment of the gastrointestinal epithelial barrier function of the host affects the colonization and distribution of gastrointestinal microorganisms. This review summarizes the structure and function of the gastrointestinal epithelial barrier and the interaction between gastrointestinal microorganisms and gastrointestinal epithelial barrier. Aiming to provide reference for the study of the relationship between gastrointestinal microorganisms and gastrointestinal epithelial barrier.

Key words: gastrointestinal epithelial barrier, tight junction, gastrointestinal tract microor-ganisms, ruminant

CLC Number:

S811.6

DU Haidong, NA Renhua. Study on Gastrointestinal Epithelial Barrier Function and Interaction with Microorganisms in Ruminants[J]. Acta Veterinaria et Zootechnica Sinica, 2023, 54(5): 1804-1814.

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Study on Gastrointestinal Epithelial Barrier Function and Interaction with Microorganisms in Ruminants

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